AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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COW-VJI6CCVRX

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesBos taurus LocusTRB TypeV FunctionalNone Length287 nt

TRBV16*01: a Bos taurus TRB V allele sequence, 287 nt, not recorded. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesBos taurus (NCBITAXON:9913)
Locus / typeTRB / V
Functional iNone
Length287 nt
Protein UID iCOW-VP-4DKNEZ (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

287 nt
GAGGCAGAAGTCACCCAGACTCCAGGGCACCTGGTTCAAGGGAAAGGACTGGAAGTGAAAATGTATTGTGTTCCCAAAAAAGGACATATTTATGTGTTCTGGTATCAGCAGATCCTGACCAAAGAGTTCAAGTTCTTGATTTCCTTCCAAAATGATAAAGTCTTGGATGATAAAGAGATGCCCAAGAGATTTTCAGCTGAGTGCCCCTCAAACTCACCTTGTAGTCTGAAGATCCAGTCTACGGAGCCGCAGGACTCAGCTTTGTATTTCTGTGCCAGCAGTGATTG

Amino-acid sequence (V-REGION)

95 aa
EAEVTQTPGHLVQGKGLEVKMYCVPKKGHIYVFWYQQILTKEFKFLISFQNDKVLDDKEMPKRFSAECPSNSPCSLKIQSTEPQDSALYFCASSD

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (COW-VJI6CCVRX). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
TRBV16*01 IMGT IMGT

External records i

IMGT: TRBV16*01

Literature references 21 total · 21 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
22792299 Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets. name mentioned* literature_supp
26962778 High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire. name mentioned* literature_supp
27460926 Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq. name mentioned* literature_supp
31237075 Comparative analysis of CDR3 regions in paired human αβ CD8 T cells. name mentioned* literature_supp
32040512 Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering. name mentioned* literature_supp
32868763 Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells. name mentioned* literature_supp
36408799 SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells. name mentioned* literature_supp
36476997 Comparing T cell receptor repertoires using optimal transport. name mentioned* literature_supp
38304555 SARS-CoV-2-associated T-cell infiltration in the central nervous system. name mentioned* literature_supp
38352870 Single-cell RNA sequencing reveals the dynamics and heterogeneity of lymph node immune cells during acute and chronic viral infections. name mentioned* literature_supp
38658646 De novo identification of CD4+ T cell epitopes. name mentioned* literature_supp
38762584 Invariant γδTCR natural killer-like effector T cells in the naked mole-rat. name mentioned* literature_supp
38871688 Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas. name mentioned* literature_supp
38878776 Quantifiable TCR repertoire changes in prediagnostic blood specimens among patients with high-grade ovarian cancer. name mentioned* literature_supp
39133650 Expansion of the HSV-2-specific T cell repertoire in skin after immunotherapeutic HSV-2 vaccine. name mentioned* literature_supp
39421738 scRNA+TCR-seq reveals the pivotal role of dual receptor T lymphocytes in the pathogenesis of Kawasaki disease and during IVIG treatment. name mentioned* literature_supp
40664667 High-resolution mapping of single cells in spatial context. name mentioned* literature_supp
40866291 Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer. name mentioned* literature_supp
41150899 Large-Scale T-cell Receptor Repertoire Profiling Unveils Tumor-Specific Signals for Diagnosing Indeterminate Pulmonary Nodules. name mentioned* literature_supp
41424382 Identification of Sjögren's disease-associated T cell receptor motifs through deep sequencing. name mentioned* literature_supp
42129543 One-step generation of T-cell receptor knock-in mice in the TCRβ locus. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGAGAAATACCGGCTAAGCTTAATGCACACTCA IMGT COW-RVKGJP

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ACGAACCCCACACTCACCTGCTTCACAGTGCTTTGTCTCCTGGGTGCAGGTTTCCTT 49 + 8 nt IMGT COW-LTYW4V

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/COW-VJI6CCVRX/similar?min_identity=0.95&kind=nt.