AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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COW-VPIMY4ODE

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesBos taurus LocusTRB TypeV FunctionalTrue Length290 nt

TRBV12-2*01: a Bos taurus TRB V allele sequence, 290 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesBos taurus (NCBITAXON:9913)
Locus / typeTRB / V
Functional iTrue
Length290 nt
Protein UID iCOW-VP-YX7OIN (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

290 nt
GATGCTGGAGTCACCCAGACCCCTAGGCATGAGGTGACAGAAAAGGGACAGGCGGTCACTCTGAGTTGTGAGCCGATTAAAAGCCACGCTGCCCTTTTTTGGTACAGACAGACCTCGGTGCGGGGACTGGAGCTGCTGATTTATTTCAACAACCAAGCTCCTATTGATGAGTCGGGGATGCCCAAGGACCGATTCTCAGCTAAGATGCATAACGCGTCATTCTCCACTCTGAAGATCCAGCCCACAGATCCTGGGGACTCAGCCACGTACCTCTGTGCCAGCAGCAAAGA

Amino-acid sequence (V-REGION)

96 aa
DAGVTQTPRHEVTEKGQAVTLSCEPIKSHAALFWYRQTSVRGLELLIYFNNQAPIDESGMPKDRFSAKMHNASFSTLKIQPTDPGDSATYLCASSK

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (COW-VPIMY4ODE). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
TRBV12-2*01 IMGT IMGT

External records i

IMGT: TRBV12-2*01

Literature references 6 total · 6 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
32868763 Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells. name mentioned* literature_supp
36408799 SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells. name mentioned* literature_supp
38658646 De novo identification of CD4+ T cell epitopes. name mentioned* literature_supp
38871688 Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas. name mentioned* literature_supp
39421738 scRNA+TCR-seq reveals the pivotal role of dual receptor T lymphocytes in the pathogenesis of Kawasaki disease and during IVIG treatment. name mentioned* literature_supp
41941497 Pigs lacking Natural Killer T cells have altered cellular responses to influenza. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGCGCTACAGAGTTGCCCCCTCCCGAGCAGAAAACC IMGT COW-RIWTPX

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGCCACCAAGCTCCTCTGCTGTGTGGCCCTGTGTCTCCTGGGAGTAGGGCCCACA 49 + 8 nt IMGT COW-L4IT46

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/COW-VPIMY4ODE/similar?min_identity=0.95&kind=nt.