AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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CYNO-VA33D7OKI

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMacaca fascicularis LocusIGH TypeV FunctionalTrue Length296 nt

IGHV1-1*01: a Macaca fascicularis IGH V allele sequence, 296 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesMacaca fascicularis (NCBITAXON:9541)
Locus / typeIGH / V
Functional iTrue
Length296 nt
Protein UID iCYNO-VP-ARWW4D (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

296 nt
CAGGTGCAGCTGGTGCAGTCTGGGGCTGAGATTAAGCAGCCTGGGGCCTCAGTGAAGCTCTCCTGCAAGGCTTCTGGATATACCTTCACTAGCTACTACATGCACTGGGTGAGACAGGCCCCTGGACAAGGCCTTGAGTGGATAGGACTGATCTCCCCTTACAATGGTAACAAAGGCTACGCACAGAACTTCCAGGGCAGAGTCACCATAACTACGGACACGTCCACGAGCACAGGCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACAGCCGTGTATTACTGTACAAGAGA

Amino-acid sequence (V-REGION)

98 aa
QVQLVQSGAEIKQPGASVKLSCKASGYTFTSYYMHWVRQAPGQGLEWIGLISPYNGNKGYAQNFQGRVTITTDTSTSTGYMELSSLRSEDTAVYYCTR

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (CYNO-VA33D7OKI). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV1-1*01 IMGT IMGT

External records i

IMGT: IGHV1-1*01

Literature references 8 total · 3 sequence-in-paper · 5 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
32866207 Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. sequence in paper literature_supp
35419009 Addressing IGHV Gene Structural Diversity Enhances Immunoglobulin Repertoire Analysis: Lessons From Rhesus Macaque. sequence in paper literature_supp
39068149 Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques. sequence in paper literature_supp
27867380 IMPre: An Accurate and Efficient Software for Prediction of T- and B-Cell Receptor Germline Genes and Alleles from Rearranged Repertoire Data. name mentioned* literature_supp
29545792 Coupling of Single Molecule, Long Read Sequencing with IMGT/HighV-QUEST Analysis Expedites Identification of SIV gp140-Specific Antibodies from scFv Phage Display Libraries. name mentioned* literature_supp
36569888 Chickens, more than humans, focus the diversity of their immunoglobulin genes on the complementarity-determining region but utilise amino acids, indicative of a more cross-reactive antibody repertoire. name mentioned* literature_supp
36604758 Bacteroides-derived isovaleric acid enhances mucosal immunity by facilitating intestinal IgA response in broilers. name mentioned* literature_supp
38567069 Diversification of immunoglobulin genes by gene conversion in the domestic chicken (Gallus gallus domesticus). name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGTGAAAACCACATCCTGAGAGTGTCAGAAACC IMGT CYNO-R64W3P

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGACTTGACCTGGAAGATCCTCCTCTTGGTGACAGCAGCCACAGGTGCCCACTCC 46 + 11 nt IMGT CYNO-L666OK

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/CYNO-VA33D7OKI/similar?min_identity=0.95&kind=nt.