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DOG-VTVFFOILZ

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesCanis lupus LocusIGH TypeV FunctionalTrue Length293 nt

IGHV3-6*01: a Canis lupus IGH V allele sequence, 293 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesCanis lupus (NCBITAXON:9612)
Locus / typeIGH / V
Functional iTrue
Length293 nt
Protein UID iDOG-VP-24AR77 (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

293 nt
GAGGTGCAGCTGGTGGAGTCTGGGGGAGACCTGGTGAAGCCTGGGGGGTCCCTGAGACTCTCCTGTGTAGCCTCTGGATTCACCTTCAGTAGCTCCGACATGAGCTGGATCCGCCAGGCTCCAGGAAAGGGGCTTCAGTGGGTCGCATACATTAGCAATGATGGAAGTAGCACAAGCTACGCAGACGCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACACGCTCTATCTGCAGATGAACAGCCTCAGAGCCGAGGACACGGCCGTGTATTACTGTGCAGA

Amino-acid sequence (V-REGION)

97 aa
EVQLVESGGDLVKPGGSLRLSCVASGFTFSSSDMSWIRQAPGKGLQWVAYISNDGSSTSYADAVKGRFTISRDNAKNTLYLQMNSLRAEDTAVYYCA

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (DOG-VTVFFOILZ). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV3-6*01 IMGT IMGT

External records i

IMGT: IGHV3-6*01

Literature references 11 total · 11 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
29545810 Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification. name mentioned* literature_supp
36328595 Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing. name mentioned* literature_supp
36473496 Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination. name mentioned* literature_supp
37938344 Role of affinity in plasma cell development in the germinal center light zone. name mentioned* literature_supp
38264661 Effect of BAFF blockade on the B cell receptor repertoire and transcriptome in a mouse model of systemic lupus erythematosus. name mentioned* literature_supp
38649520 Single-cell T-cell receptor repertoire profiling in dogs. name mentioned* literature_supp
38961347 Systematic characterization of immunoglobulin loci and deep sequencing of the expressed repertoire in the Atlantic cod (Gadus morhua). name mentioned* literature_supp
39698082 Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten. name mentioned* literature_supp
40338637 Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein. name mentioned* literature_supp
41410768 Convergent mutation trajectories convert functional self-tolerance in IGHV4-34 B cells to genetic tolerance encoded in the antibody. name mentioned* literature_supp
41876881 Development of canine parvovirus-neutralizing monoclonal antibodies from natural host and their germline gene usage. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/DOG-VTVFFOILZ/similar?min_identity=0.95&kind=nt.