AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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HORSE-V7UR3BDVA

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesEquus caballus LocusIGH TypeV FunctionalNone Length292 nt

IGHV1-45*01: a Equus caballus IGH V allele sequence, 292 nt, not recorded. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesEquus caballus (NCBITAXON:9796)
Locus / typeIGH / V
Functional iNone
Length292 nt
Protein UID iHORSE-VP-GPQCKL (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

292 nt
CAGATCCAGCTGGTGCAGTCTGGGGCTGAGGTAAAGAAGCCTGGGTCAACAGTGAAGCTCTCCTGCAAGGCTTCTGGATACACCTTCACTGACTATGCTATGCACTGGTTGTGACAGGCCCCTGGAAAAGGGCTTGAGTGGATGGGATATATCTATCCCAAGATGATGATGCAAGCTACGCACAGAAGTTCCCGGCAGAGTCACTATGACTGTGGACTTGTCCACGAGCACAGTCTACATGGAGCTGATCAGTCTGAGATCTGAGGACACGGCTGTGTATTACGGTGCGAGA

Amino-acid sequence (V-REGION)

97 aa
QIQLVQSGAEVKKPGSTVKLSCKASGYTFTDYAMHWL*QAPGKGLEWMGYIYPKMMMQATHRSSRQSHYDCGLVHEHSLHGADQSEI*GHGCVLRCE

Translated here from the nucleotide sequence; no source published a protein for this allele. i

Name history i: formerly IGHV1-54*01 (to 2020-01-31);

Allele names i

Every name below denotes this exact sequence (HORSE-V7UR3BDVA). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV1-45*01 IMGT IMGT

Former IMGT names i

Former nameLast seen in IMGT release
IGHV1-54*012020-01-31

External records i

IMGT: IGHV1-45*01

Literature references 9 total · 9 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
29558968 BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data. name mentioned* literature_supp
32636395 IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms. name mentioned* literature_supp
36328595 Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing. name mentioned* literature_supp
36604758 Bacteroides-derived isovaleric acid enhances mucosal immunity by facilitating intestinal IgA response in broilers. name mentioned* literature_supp
39840032 An allelic atlas of immunoglobulin heavy chain variable regions reveals antibody binding epitope preference resilient to SARS-CoV-2 mutation escape. name mentioned* literature_supp
40066131 Characterization of Immunoglobulin Heavy Locus Rearrangements in Molecular Subtypes of Childhood B-Cell Precursor Acute Lymphoblastic Leukemia. name mentioned* literature_supp
40664667 High-resolution mapping of single cells in spatial context. name mentioned* literature_supp
41617721 Refined phenotyping of vaccine responses reveals transcriptomic determinants of neutralizing antibody heterogeneity. name mentioned* literature_supp
42078068 B-cell immune repertoire analysis of autoimmune neurological syndromes with anti-GAD65 antibodies. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCAGTGTGATAAGCCACATCCTGAGCATGTCAGAAACCCT IMGT HORSE-RMK3BC

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGACTGGAGCTGGAGAATCCTTTTCTCGGGGGCAGTGGCTACAGGTGTCCACTCA 46 + 11 nt IMGT HORSE-LGAS4T

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/HORSE-V7UR3BDVA/similar?min_identity=0.95&kind=nt.