HUMAN-V4LM6A44N
AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.
TRBV20-1*02: a Homo sapiens TRB V allele sequence, 293 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.
Earlier records of this allele i
IMGT has published this allele name over more than one sequence extent. Earlier sequence extents are deferred from default search results but remain resolvable, so a paper that cited one still leads here.
| Record | Name | Length | Relation to this record | IMGT releases |
|---|---|---|---|---|
| HUMAN-VIN3Z5IO6 | TRBV20-1*02 | 288 nt | contained in this record | 2013-01-20–2025-01-05 |
| Species | Homo sapiens (NCBITAXON:9606) |
|---|---|
| Locus / type | TRB / V |
| Functional i | True |
| Length | 293 nt |
| Protein UID i | HUMAN-VP-OI4D4Y (shared by alleles with the same V-REGION amino-acid sequence) |
Coding sequence (nt)
Amino-acid sequence (V-REGION)
Published by the source, and consistent with the nucleotide sequence above. i
Name history i: re-cut from TRBV20-1*02 (288 nt);
Allele names i
Every name below denotes this exact sequence (HUMAN-V4LM6A44N). None is canonical; they are labels, and the UID is the key.
| Name | Scheme | Source(s) |
|---|---|---|
| TRBV20-1*02 | IMGT | IMGT |
Other names & identifiers
Alternative and former names, e.g. IMGT clone names, plus accession identifiers.
| Name | Kind | Source(s) |
|---|---|---|
| LR800373.1 | NCBI accession | ncbi_nucleotide |
External records i
NCBI nucleotide: link IMGT: TRBV20-1*02
Literature references i
PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.
| PMID | Title | Evidence | Source |
|---|---|---|---|
| 22792299 | Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets. | name mentioned* | literature_supp |
| 23995877 | IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling. | name mentioned* | literature_supp |
| 26962778 | High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire. | name mentioned* | literature_supp |
| 34991709 | T cell receptor beta germline variability is revealed by inference from repertoire data. | name mentioned* | literature_supp |
| 36408799 | SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells. | name mentioned* | literature_supp |
| 37287989 | Targeting KRASG12V mutations with HLA class II-restricted TCR for the immunotherapy in solid tumors. | name mentioned* | literature_supp |
| 38615042 | Deep learning predictions of TCR-epitope interactions reveal epitope-specific chains in dual alpha T cells. | name mentioned* | literature_supp |
| 38871688 | Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas. | name mentioned* | literature_supp |
| 39421738 | scRNA+TCR-seq reveals the pivotal role of dual receptor T lymphocytes in the pathogenesis of Kawasaki disease and during IVIG treatment. | name mentioned* | literature_supp |
| 39472557 | Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes. | name mentioned* | literature_supp |
| 42125653 | N-terminal pyroglutamylation of an HLA-A24-restricted immunodominant epitope enhances SARS-CoV-2-specific T-cell responses. | name mentioned* | literature_supp |
* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.
Contributed by IMGT, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.
RSS i
Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.
| Part | Sequence | Source | RSS UID |
|---|---|---|---|
| v_rs | CACAGCGCCAGGAGGGGATCAGACACCGCGGCAAGAACC | IMGT | HUMAN-RCP4FP |
Leader
Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.
| Leader (exon 1 + exon 2) | Split | Source | Leader UID |
|---|---|---|---|
| ATGCTGCTGCTTCTGCTGCTTCTGGGGCCAGGTATAAGCCTCCTTCTACCTGGGAGCTTGGCAGGCTCCGGGCTT | 61 + 14 nt | IMGT | HUMAN-LBQWTV |
Find similar (nt · aa · cross-species) i
Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.
Ranks coding alleles by normalized edit-distance identity.
Also available at /api/sequences/HUMAN-V4LM6A44N/similar?min_identity=0.95&kind=nt.
API: JSON · AIRR AlleleDescription · aliases