AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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HUMAN-VCGRRCI4S

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesHomo sapiens LocusIGK TypeV FunctionalFalse Length302 nt

IGKV2-18*01: a Homo sapiens IGK V allele sequence, 302 nt, non-functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

Earlier records of this allele i

IMGT has published this allele name over more than one sequence extent. Earlier sequence extents are deferred from default search results but remain resolvable, so a paper that cited one still leads here.

RecordNameLengthRelation to this recordIMGT releases
HUMAN-V5BKQGBFH IGKV2-18*01 300 nt contained in this record 2013-01-20
SpeciesHomo sapiens (NCBITAXON:9606)
Locus / typeIGK / V
Functional iFalse
Length302 nt
Protein UID iHUMAN-VP-JB2MBE (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

302 nt
GATATTGTGATGACCCAGACTCCACCCTCCCTGCCCGTCAACCCTGGAGAGCCGGCCTCCATCTCTTGCAGGTCTAGTCAGAGCCTCCTGCATAGTAATGGATATACCTATTTGCATTGGTACCTGCAGAAGCCAGGGCAGTCTCCACAGCTCCTGATTTATAGGGTTTCCAATCATCTTTCTGGGGTCCCAGACAGGTTTAGTGGCAGTGGGTCAGGTAGTGATTTCACACTGAAAATCAGCTGGGTGGAGGCTGAGGATGTTGGGGTTTATTACTGCATGCAAGCTACACAGTTTCCTAA

Amino-acid sequence (V-REGION)

100 aa
DIVMTQTPPSLPVNPGEPASISCRSSQSLLHSNGYTYLHWYLQKPGQSPQLLIYRVSNHLSGVPDRFSGSGSGSDFTLKISWVEAEDVGVYYCMQATQFP

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: re-cut from IGKV2-18*01 (300 nt);

Allele names i

Every name below denotes this exact sequence (HUMAN-VCGRRCI4S). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGKV2-18*01 IMGT IMGT, OGRDB

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
X63400.1 NCBI accession ncbi_nucleotide

External records i

NCBI nucleotide: link GenBank: GENBANK:X63400 GenBank: GENBANK:X63400.1 IMGT: IGKV2-18*01 OGRDB: IGKV2-18*01

Literature references 6 total · 1 verified · 5 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
1551402 verified ncbi_nucleotide
31839985 More than one antibody of individual B cells revealed by single-cell immune profiling. name mentioned* literature_supp
35383174 Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci. name mentioned* literature_supp
36328595 Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing. name mentioned* literature_supp
39833978 Characterization of the colostrum proteome of primiparous Holstein cows and its association with colostrum immunoglobulin G concentrations. name mentioned* literature_supp
41803327 IFN-gene signatures in B cells following influenza A and B virus infection and influenza vaccination. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, OGRDB, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGGTACAACCCTGAACAGAAACC IMGT HUMAN-RUSEBD

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATAAGGGTCCCTGCTCAGCTCCTGGGGCTGCTAATGCTTTGGGTTCCTGGATCCAGTGGA 49 + 11 nt IMGT HUMAN-LRC5U2

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/HUMAN-VCGRRCI4S/similar?min_identity=0.95&kind=nt.