AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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HUMAN-VFDTSVNQO

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesHomo sapiens LocusIGK TypeV FunctionalFalse Length287 nt

IGKV1D-42*02: a Homo sapiens IGK V allele sequence, 287 nt, non-functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesHomo sapiens (NCBITAXON:9606)
Locus / typeIGK / V
Functional iFalse
Length287 nt
Protein UID iHUMAN-VP-YRHRRB (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

287 nt
GACATCCAGATGACCCAGTCTCCATCTTTCCTGTCTGCATCTGTAGGAGACAGAGTCAGTATCATTTGCTGGGCAAGTGAGGGCATTAGCAGTAATTTAGCCTGGTATCTGCAGAAACCAGGGAAATCCCCTAAGCTCTTCCTCTATGATGCAAAAGATTTGCACCCTGGGGTCTCATCGAGGTTCAGTGGCAGGGGATCTGGGACGGATTTCACTCTCACCATCATCAGCCTGAAGCCTGAAGATTTTGCAGCTTATTACTGTAAACAGGACTTCAGTTACCCTCC

Amino-acid sequence (V-REGION)

95 aa
DIQMTQSPSFLSASVGDRVSIICWASEGISSNLAWYLQKPGKSPKLFLYDAKDLHPGVSSRFSGRGSGTDFTLTIISLKPEDFAAYYCKQDFSYP

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (HUMAN-VFDTSVNQO). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGKV1D-42*02 IMGT IMGT, OGRDB

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
KM455560.1 NCBI accession ncbi_nucleotide

External records i

NCBI nucleotide: link GenBank: GENBANK:KM455560 GenBank: GENBANK:KM455560.1 IMGT: IGKV1D-42*02 OGRDB: IGKV1D-42*02

Literature references 4 total · 1 verified · 1 sequence-in-paper · 2 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
25338678 Sequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversity. verified ncbi_nucleotide
38844673 Resolving haplotype variation and complex genetic architecture in the human immunoglobulin kappa chain locus in individuals of diverse ancestry. sequence in paper literature_supp
33048842 Antimalarial antibody repertoire defined by plasma IG proteomics and single B cell IG sequencing. name mentioned* literature_supp
40664667 High-resolution mapping of single cells in spatial context. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, OGRDB, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGGGTTACAAGCCTGAACATAAGCC IMGT HUMAN-RIBP3B

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGAGGGTCCCCGCTCAGCTCCTGGGGCTCCTGCTGCTCTGGCTCCCAGGTGTCAGATTT 49 + 11 nt IMGT HUMAN-L77QNH

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/HUMAN-VFDTSVNQO/similar?min_identity=0.95&kind=nt.