AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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HUMAN-VGL5MKJAT

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesHomo sapiens LocusIGH TypeV FunctionalTrue Length299 nt

IGHV4-39*01_S2720, IGHV4-39*10, IGHV4-39*i03: a Homo sapiens IGH V allele sequence, 299 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesHomo sapiens (NCBITAXON:9606)
Locus / typeIGH / V
Functional iTrue
Length299 nt
Protein UID iHUMAN-VP-7CDUJ5 (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

299 nt
CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCAAGACA

Amino-acid sequence (V-REGION)

99 aa
QLQLQESGPGLVKPSETLSLTCTVSGGSISSSSYYWGWIRQPPGKGLEWIGSIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCAR

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (HUMAN-VGL5MKJAT). None is canonical; they are labels, and the UID is the key.

Multiple allele designations. This one sequence is recorded under 3 different allele designations: IGHV4-39*01_S2720, IGHV4-39*10, IGHV4-39*i03. These are identical normalized nucleotide sequences with different attributed names.

NameSchemeSource(s)
IGHV4-39*01_S2720 IgDiscover KIARVA
IGHV4-39*10 IMGT IMGT
IGHV4-39*i03 OGRDB OGRDB

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
BK070982.1 NCBI accession ncbi_nucleotide

External records i

NCBI nucleotide: link GenBank: GENBANK:BK070982 GenBank: GENBANK:BK070982.1 IMGT: IGHV4-39*10 OGRDB: IGHV4-39*i03

Literature references 3 total · 2 verified · 1 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
34875068 verified ncbi_nucleotide
40977881 verified ncbi_nucleotide
36798124 Analysis of IGH allele content in a sample group of rheumatoid arthritis patients demonstrates unrevealed population heterogeneity. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, KIARVA, OGRDB, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGAGGGGAGGTGAGTGTGAGCCCAGACAAAAACC IMGT HUMAN-RAIL2W

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGAAGCACCTGTGGTTCTTCCTCCTGCTGGTGGCGGCTCCCAGATGGGTCCTGTCC 46 + 11 nt IMGT HUMAN-LQU5BQ

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/HUMAN-VGL5MKJAT/similar?min_identity=0.95&kind=nt.