HUMAN-VW2EAECQQ
AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.
TRBV19*03: a Homo sapiens TRB V allele sequence, 287 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.
Earlier records of this allele i
IMGT has published this allele name over more than one sequence extent. Earlier sequence extents are deferred from default search results but remain resolvable, so a paper that cited one still leads here.
| Record | Name | Length | Relation to this record | IMGT releases |
|---|---|---|---|---|
| HUMAN-VPNEFSDBL | TRBV19*03 | 282 nt | bases differ | 2013-01-20 |
| HUMAN-VKOP5IMPP | TRBV19*03 | 281 nt | contained in this record | 2015-03-19–2025-01-05 |
| Species | Homo sapiens (NCBITAXON:9606) |
|---|---|
| Locus / type | TRB / V |
| Functional i | True |
| Length | 287 nt |
| Protein UID i | HUMAN-VP-2GPY4B (shared by alleles with the same V-REGION amino-acid sequence) |
Coding sequence (nt)
Amino-acid sequence (V-REGION)
Published by the source, and consistent with the nucleotide sequence above. i
Name history i: re-cut from TRBV19*03 (282 nt); re-cut from TRBV19*03 (281 nt);
Allele names i
Every name below denotes this exact sequence (HUMAN-VW2EAECQQ). None is canonical; they are labels, and the UID is the key.
| Name | Scheme | Source(s) |
|---|---|---|
| TRBV19*03 | IMGT | IMGT |
External records i
IMGT: TRBV19*03
Literature references i
PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.
| PMID | Title | Evidence | Source |
|---|---|---|---|
| 26962778 | High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire. | name mentioned* | literature_supp |
| 27460926 | Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq. | name mentioned* | literature_supp |
| 35436998 | pmTR database: population matched (pm) germline allelic variants of T-cell receptor (TR) loci. | name mentioned* | literature_supp |
| 36408799 | SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells. | name mentioned* | literature_supp |
| 36923729 | Cross-reactivity influences changes in human influenza A virus and Epstein Barr virus specific CD8 memory T cell receptor alpha and beta repertoires between young and old. | name mentioned* | literature_supp |
| 38615042 | Deep learning predictions of TCR-epitope interactions reveal epitope-specific chains in dual alpha T cells. | name mentioned* | literature_supp |
| 39472557 | Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes. | name mentioned* | literature_supp |
* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.
Contributed by IMGT. See Sources & citations for each source's version, citation and licence.
RSS i
Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.
| Part | Sequence | Source | RSS UID |
|---|---|---|---|
| v_rs | CACAGTGAAGCACGGATGTCGCCTCTCTGTGCATAAATG | IMGT | HUMAN-RYLQJY |
Leader
Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.
| Leader (exon 1 + exon 2) | Split | Source | Leader UID |
|---|---|---|---|
| ATGAGCAACCAGGTGCTCTGCTGTGTGGTCCTTTGTCTCCTGGGAGCAAACACCGTG | 49 + 8 nt | IMGT | HUMAN-LK2Q2Y |
Find similar (nt · aa · cross-species) i
Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.
Ranks coding alleles by normalized edit-distance identity.
Also available at /api/sequences/HUMAN-VW2EAECQQ/similar?min_identity=0.95&kind=nt.
API: JSON · AIRR AlleleDescription · aliases