AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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HUMAN-VZ6TBMPRO

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesHomo sapiens LocusIGH TypeV FunctionalTrue Length301 nt

IGHV2-70*05: a Homo sapiens IGH V allele sequence, 301 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

Earlier records of this allele i

IMGT has published this allele name over more than one sequence extent. Earlier sequence extents are deferred from default search results but remain resolvable, so a paper that cited one still leads here.

RecordNameLengthRelation to this recordIMGT releases
HUMAN-V2AHS3KN5 IGHV2-70*05 237 nt contained in this record 2013-01-20–2023-02-20
SpeciesHomo sapiens (NCBITAXON:9606)
Locus / typeIGH / V
Functional iTrue
Length301 nt
Protein UID iHUMAN-VP-PSXGJU (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

301 nt
CAGGTCACCTTGAAGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGCGTGCGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACGCATTGATTGGGATGATGATAAATTCTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATAC

Amino-acid sequence (V-REGION)

100 aa
QVTLKESGPALVKPTQTLTLTCTFSGFSLSTSGMRASWIRQPPGKALEWLARIDWDDDKFYSTSLKTRLTISKDTSKNQVVLTMTNMDPVDTATYYCARI

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: re-cut from IGHV2-70*05 (237 nt);

Allele names i

Every name below denotes this exact sequence (HUMAN-VZ6TBMPRO). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV2-70*05 IMGT IMGT, KIARVA, OGRDB

External records i

GenBank: GENBANK:IMGT000129 IMGT: IGHV2-70*05 OGRDB: IGHV2-70*05

Literature references 5 total · 2 sequence-in-paper · 3 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
37114042 Adaptive immune receptor genotyping using the corecount program. sequence in paper literature_supp
38643233 An ancestral SARS-CoV-2 vaccine induces anti-Omicron variants antibodies by hypermutation. sequence in paper literature_supp
33048842 Antimalarial antibody repertoire defined by plasma IG proteomics and single B cell IG sequencing. name mentioned* literature_supp
34484220 RAPID: A Rep-Seq Dataset Analysis Platform With an Integrated Antibody Database. name mentioned* literature_supp
34764956 Novel Allele Detection Tool Benchmark and Application With Antibody Repertoire Sequencing Dataset. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, KIARVA, OGRDB. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGAGACACAGCCCAGGGCGCCTCCTGTACAAGAACC IMGT HUMAN-R5MGF5

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGACATACTTTGTTCCACGCTCCTGCTACTGACTGTCCCGTCCTGGGTCTTATCC 46 + 11 nt IMGT HUMAN-LD3EB2

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/HUMAN-VZ6TBMPRO/similar?min_identity=0.95&kind=nt.