AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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LEMUR-V6QPB6DR6

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesLemur catta LocusIGH TypeV FunctionalTrue Length296 nt

IGHV3-49*01: a Lemur catta IGH V allele sequence, 296 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesLemur catta (NCBITAXON:9447)
Locus / typeIGH / V
Functional iTrue
Length296 nt
Protein UID iLEMUR-VP-6FJ2R7 (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

296 nt
GAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGATCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTCAGCAGCTACTGGATGCATTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGGAGACATCAATGGTAATGATGGTAGCACATACTACGCAGACGCCGTGAAGGGCCGATTCACCATCTCCAGAGACAACGGCAAGAACACGCTGTCTCTGCAAATGAACAGTCTGAGAGCCGAGGACACGGCCCTGTACTACTGTGCCAGAGA

Amino-acid sequence (V-REGION)

98 aa
EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYWMHWVRQAPGKGLEWVGDINGNDGSTYYADAVKGRFTISRDNGKNTLSLQMNSLRAEDTALYYCAR

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (LEMUR-V6QPB6DR6). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV3-49*01 IMGT IMGT

External records i

IMGT: IGHV3-49*01

Literature references 9 total · 9 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
31839985 More than one antibody of individual B cells revealed by single-cell immune profiling. name mentioned* literature_supp
33843586 Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth. name mentioned* literature_supp
36328595 Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing. name mentioned* literature_supp
38435425 Analysis of immunoglobulin/T-cell receptor repertoires by high-throughput RNA sequencing reveals a continuous dynamic of positive clonal selection in follicular lymphoma. name mentioned* literature_supp
38961347 Systematic characterization of immunoglobulin loci and deep sequencing of the expressed repertoire in the Atlantic cod (Gadus morhua). name mentioned* literature_supp
40066131 Characterization of Immunoglobulin Heavy Locus Rearrangements in Molecular Subtypes of Childhood B-Cell Precursor Acute Lymphoblastic Leukemia. name mentioned* literature_supp
40664667 High-resolution mapping of single cells in spatial context. name mentioned* literature_supp
41617721 Refined phenotyping of vaccine responses reveals transcriptomic determinants of neutralizing antibody heterogeneity. name mentioned* literature_supp
42078068 B-cell immune repertoire analysis of autoimmune neurological syndromes with anti-GAD65 antibodies. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGAGGGGACATCAGTGTGAGCCCAGACACAAACC IMGT LEMUR-R2JQKZ

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGAGTCTGGGCTGTGCTGGGTTTTCCTTGTTGCTCTGTTACAAGGTGTCCAGTGT 46 + 11 nt IMGT LEMUR-LTSXAU

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/LEMUR-V6QPB6DR6/similar?min_identity=0.95&kind=nt.