AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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MOUSE-V3HWDBFOU

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMus musculus LocusIGH TypeV FunctionalTrue Length293 nt

IGHV2-6*01, IGHV2-6-8*01: a Mus musculus IGH V allele sequence, 293 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

Earlier records of this allele i

IMGT has published this allele name over more than one sequence extent. Earlier sequence extents are deferred from default search results but remain resolvable, so a paper that cited one still leads here.

RecordNameLengthRelation to this recordIMGT releases
MOUSE-VA2K66X7G IGHV2-6*01 292 nt contained in this record 2013-01-20
SpeciesMus musculus (NCBITAXON:10090)
Locus / typeIGH / V
Functional iTrue
Length293 nt
Protein UID iMOUSE-VP-4RNWDG (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

293 nt
CAGGTGCAGCTGAAGGAGTCAGGACCTGGCCTGGTGGCGCCCTCACAGAGCCTGTCCATCACATGCACTGTCTCTGGGTTCTCATTAACCAGCTATGGTGTAGACTGGGTTCGCCAGTCTCCAGGAAAGGGTCTGGAGTGGCTGGGAGTAATATGGGGTGTTGGAAGCACAAATTATAATTCAGCTCTCAAATCCAGACTGAGCATCAGCAAGGACAACTCCAAGAGCCAAGTTTTCTTAAAAATGAACAGTCTGCAAACTGATGACACAGCCATGTACTACTGTGCCAGTGA

Amino-acid sequence (V-REGION)

97 aa
QVQLKESGPGLVAPSQSLSITCTVSGFSLTSYGVDWVRQSPGKGLEWLGVIWGVGSTNYNSALKSRLSISKDNSKSQVFLKMNSLQTDDTAMYYCAS

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: re-cut from IGHV2-6*01 (292 nt);

Allele names i

Every name below denotes this exact sequence (MOUSE-V3HWDBFOU). None is canonical; they are labels, and the UID is the key.

Multiple allele designations. This one sequence is recorded under 2 different allele designations: IGHV2-6*01, IGHV2-6-8*01. These are identical normalized nucleotide sequences with different attributed names.

NameSchemeSource(s)
IGHV2-6*01 IMGT IMGT
IGHV2-6-8*01 IMGT IMGT

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
BN000872.1 NCBI accession ncbi_nucleotide

External records i

NCBI nucleotide: link GenBank: GENBANK:BN000872 GenBank: GENBANK:BN000872.1 GenBank: GENBANK:CAAA01078923 IMGT: IGHV2-6*01

Literature references 6 total · 1 verified · 5 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
16547259 verified ncbi_nucleotide
35720344 A BALB/c IGHV Reference Set, Defined by Haplotype Analysis of Long-Read VDJ-C Sequences From F1 (BALB/c x C57BL/6) Mice. name mentioned* literature_supp
38264661 Effect of BAFF blockade on the B cell receptor repertoire and transcriptome in a mouse model of systemic lupus erythematosus. name mentioned* literature_supp
39698082 Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten. name mentioned* literature_supp
40981271 Cost-Effective Method for Full-Length Sequencing of Monoclonal Antibodies from Hybridoma Cells. name mentioned* literature_supp
41410768 Convergent mutation trajectories convert functional self-tolerance in IGHV4-34 B cells to genetic tolerance encoded in the antibody. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGAGGGAAGTCCAATGTGAGCCTGCACAAATACT IMGT MOUSE-RZ3SKO

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGCTGTCCTGGCGCTACTCCTCTGCCTGGTGACTTTCCCAAGCTGTATCCTTTCC 46 + 11 nt IMGT MOUSE-LWSPKN

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/MOUSE-V3HWDBFOU/similar?min_identity=0.95&kind=nt.