AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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MOUSE-V425JKO46

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMus musculus LocusIGK TypeV FunctionalTrue Length292 nt

IGKV4-51*01: a Mus musculus IGK V allele sequence, 292 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesMus musculus (NCBITAXON:10090)
Locus / typeIGK / V
Functional iTrue
Length292 nt
Protein UID iMOUSE-VP-JMKIK6 (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

292 nt
GAAAATGTGCTCACCCAGTCTCCAGCAATAATGGCTGCCTCTCTGGGGGAGAAGGTCACCATGACCTGCAGTGCCAGCTCAAGTGTAAGTTCCAGCTACTTGCACTGGTACCAGCAGAAGTCAGGCACTTCCCCCAAACTCTGGATTTATGGCACATCCAACCTGGCTTCTGGAGTCCCAGCTCGCTTCAGTGGCAGTGGGGCTGGGATCTCTTACTCTCTCACAATCAGCAGCATGGAGGCTGAAAATGATGCAACTTATTACTGCCAGCAGTGGAGTGGTTACCCATTCA

Amino-acid sequence (V-REGION)

97 aa
ENVLTQSPAIMAASLGEKVTMTCSASSSVSSSYLHWYQQKSGTSPKLWIYGTSNLASGVPARFSGSGAGISYSLTISSMEAENDATYYCQQWSGYPF

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (MOUSE-V425JKO46). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGKV0-5FLR*00 IgLabel OGRDB
IGKV4-51*01 IMGT IMGT

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
V01565.1 NCBI accession ncbi_nucleotide

External records i

NCBI nucleotide: link GenBank: GENBANK:V01565 GenBank: GENBANK:V01565.1 IMGT: IGKV4-51*01 OGRDB: IGKV0-5FLR*00

Literature references 5 total · 2 verified · 3 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
6253944 verified ncbi_nucleotide
6803241 verified ncbi_nucleotide
28899929 Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens. name mentioned* literature_supp
36473496 Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination. name mentioned* literature_supp
41410768 Convergent mutation trajectories convert functional self-tolerance in IGHV4-34 B cells to genetic tolerance encoded in the antibody. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, OGRDB, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGCTACAGACTGGAACAAAAACA IMGT MOUSE-R3OZKI

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGATTTACAGGTGCAGATTATCAGCTTCCTGCTAATCATTGTCACAGTCATAATGTCCAGAGGA 49 + 17 nt IMGT MOUSE-LR5UVH

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/MOUSE-V425JKO46/similar?min_identity=0.95&kind=nt.