AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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MOUSE-VF3CG5NBX

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMus musculus LocusIGH TypeV FunctionalFalse Length294 nt

IGHV1-8*02: a Mus musculus IGH V allele sequence, 294 nt, non-functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesMus musculus (NCBITAXON:10090)
Locus / typeIGH / V
Functional iFalse
Length294 nt
Protein UID iMOUSE-VP-6TOXWE (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

294 nt
CAGGATCAGCTACATCAGTCTGGAGCTGAGCTGCAGCAACCTGGGACATCAGTGAAGATGCCCTGCAAGGCTACTGGCTACACCTTCACTAAGTATCGAATGCGTTGGGTGAGGCAGAAGCTTGGACAGGGCCTGGAATGGATTGCATCTGTTGATCCTGGAAATAGTAATACTGAATACAATCAGAAGTTCAAAGGCAAGACCTCACTAACTGAATACAAATCCTCCAGCACAGCCTACATAGAGCTTAGCAGCCTGACCTCTGAGGACTCTGTGGTCTATTACTGTACAAGA

Amino-acid sequence (V-REGION)

98 aa
QDQLHQSGAELQQPGTSVKMPCKATGYTFTKYRMRWVRQKLGQGLEWIASVDPGNSNTEYNQKFKGKTSLTEYKSSSTAYIELSSLTSEDSVVYYCTR

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (MOUSE-VF3CG5NBX). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV1-8*02 IMGT IMGT

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
BK063713.1 NCBI accession ncbi_nucleotide

External records i

NCBI nucleotide: link GenBank: GENBANK:BK063713 GenBank: GENBANK:BK063713.1 IMGT: IGHV1-8*02

Literature references 13 total · 1 verified · 12 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
34875068 verified ncbi_nucleotide
29558968 BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data. name mentioned* literature_supp
30697215 VH1-69 Utilizing Antibodies Are Capable of Mediating Non-neutralizing Fc-Mediated Effector Functions Against the Transmitted/Founder gp120. name mentioned* literature_supp
31839985 More than one antibody of individual B cells revealed by single-cell immune profiling. name mentioned* literature_supp
32636395 IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms. name mentioned* literature_supp
33843586 Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth. name mentioned* literature_supp
34126625 Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection. name mentioned* literature_supp
34242577 In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. name mentioned* literature_supp
34785098 Landscapes and dynamic diversifications of B-cell receptor repertoires in COVID-19 patients. name mentioned* literature_supp
36328595 Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing. name mentioned* literature_supp
38435425 Analysis of immunoglobulin/T-cell receptor repertoires by high-throughput RNA sequencing reveals a continuous dynamic of positive clonal selection in follicular lymphoma. name mentioned* literature_supp
41617721 Refined phenotyping of vaccine responses reveals transcriptomic determinants of neutralizing antibody heterogeneity. name mentioned* literature_supp
42078068 B-cell immune repertoire analysis of autoimmune neurological syndromes with anti-GAD65 antibodies. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACTGTGTTAAAACCACATACTGATTGTGTCAAAAACC IMGT MOUSE-RNWQQM

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGAAGAGAGTGGTATCTTTCTCTTCCTCTTGTCAGTAACTTGAAGTGTCCACTCA 46 + 11 nt IMGT MOUSE-LQLFMR

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/MOUSE-VF3CG5NBX/similar?min_identity=0.95&kind=nt.