AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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MOUSE-VG7WJJU3N

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMus musculus LocusIGH TypeV FunctionalFalse Length294 nt

IGHV1-46*02: a Mus musculus IGH V allele sequence, 294 nt, non-functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesMus musculus (NCBITAXON:10090)
Locus / typeIGH / V
Functional iFalse
Length294 nt
Protein UID iMOUSE-VP-Z2UABI (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

294 nt
CAGGTCCAGCTGCAGCAGTCTGCAGCTGAGCTGGTGAAGCCTGGGAGTCCAGTGAAGCTGTCCTGCAAAGCTTCTGGCTACACCGTCAATGACAACTATATGGAGCAGGTAAAGCAGAGGCCTGGACAGAGCATGGAATGGATTGGATAGATTCATTTTGTATATGGTGGTACTTAATACAATGAAAAGTTCTAGGGCAAGTCCACATTAACTGTAGAAAAATCCTCCAACACAGCCTACATGGAACTCCACAGCTCAACATCTGAGGTCTCTGCGGTTTATTTCTGTGCACGG

Amino-acid sequence (V-REGION)

98 aa
QVQLQQSAAELVKPGSPVKLSCKASGYTVNDNYMEQVKQRPGQSMEWIG*IHFVYGGT*YNEKF*GKSTLTVEKSSNTAYMELHSSTSEVSAVYFCAR

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (MOUSE-VG7WJJU3N). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV1-46*02 IMGT IMGT

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
BK063713.1 NCBI accession ncbi_nucleotide

External records i

NCBI nucleotide: link GenBank: GENBANK:BK063713 GenBank: GENBANK:BK063713.1 IMGT: IGHV1-46*02

Literature references 26 total · 1 verified · 25 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
34875068 verified ncbi_nucleotide
27423190 A Single Human Papillomavirus Vaccine Dose Improves B Cell Memory in Previously Infected Subjects. name mentioned* literature_supp
29545810 Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification. name mentioned* literature_supp
29558968 BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data. name mentioned* literature_supp
30697215 VH1-69 Utilizing Antibodies Are Capable of Mediating Non-neutralizing Fc-Mediated Effector Functions Against the Transmitted/Founder gp120. name mentioned* literature_supp
31839985 More than one antibody of individual B cells revealed by single-cell immune profiling. name mentioned* literature_supp
32156260 Tracing CLL-biased stereotyped immunoglobulin gene rearrangements in normal B cell subsets using a high-throughput immunogenetic approach. name mentioned* literature_supp
32636395 IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms. name mentioned* literature_supp
33048842 Antimalarial antibody repertoire defined by plasma IG proteomics and single B cell IG sequencing. name mentioned* literature_supp
33843586 Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth. name mentioned* literature_supp
34126625 Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection. name mentioned* literature_supp
34242577 In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. name mentioned* literature_supp
34614412 mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants. name mentioned* literature_supp
34785098 Landscapes and dynamic diversifications of B-cell receptor repertoires in COVID-19 patients. name mentioned* literature_supp
34788600 Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability. name mentioned* literature_supp
35776090 Antibody evolution to SARS-CoV-2 after single-dose Ad26.COV2.S vaccine in humans. name mentioned* literature_supp
35837088 Characterizing Features of Human Circulating B Cells Carrying CLL-Like Stereotyped Immunoglobulin Rearrangements. name mentioned* literature_supp
36006380 Humoral immunity to SARS-CoV-2 elicited by combination COVID-19 vaccination regimens. name mentioned* literature_supp
36149398 Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection in humans. name mentioned* literature_supp
36328595 Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing. name mentioned* literature_supp
37368240 Memory B cell development elicited by mRNA booster vaccinations in the elderly. name mentioned* literature_supp
39840032 An allelic atlas of immunoglobulin heavy chain variable regions reveals antibody binding epitope preference resilient to SARS-CoV-2 mutation escape. name mentioned* literature_supp
41617721 Refined phenotyping of vaccine responses reveals transcriptomic determinants of neutralizing antibody heterogeneity. name mentioned* literature_supp
41803327 IFN-gene signatures in B cells following influenza A and B virus infection and influenza vaccination. name mentioned* literature_supp
42078068 B-cell immune repertoire analysis of autoimmune neurological syndromes with anti-GAD65 antibodies. name mentioned* literature_supp
42256548 Genomic heterogeneity in primary cutaneous follicular center lymphomas reveals different clinicopathological subgroups. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCAGAGTGTTATAACCACATCCTGTGTGTCTCAAAAACC IMGT MOUSE-RJCJTD

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGGATGGAGCTGGGTCTTTCTCTTCCTCCTGTCAGTAACTGCAGGTGTCCACTGC 46 + 11 nt IMGT MOUSE-LJRF7V

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/MOUSE-VG7WJJU3N/similar?min_identity=0.95&kind=nt.