AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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MOUSE-VL6UUQGIJ

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMus musculus LocusTRA TypeV FunctionalTrue Length280 nt

TRAV10*01: a Mus musculus TRA V allele sequence, 280 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesMus musculus (NCBITAXON:10090)
Locus / typeTRA / V
Functional iTrue
Length280 nt
Protein UID iMOUSE-VP-4O6624 (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

280 nt
GGAGAGAAGGTCGAGCAACACGAGTCTACACTGAGTGTTCGAGAGGGAGACAGCGCTGTCATCAACTGCACTTACACAGATACTGCTTCATCATACTTCCCTTGGTACAAGCAAGAAGCTGGAAAGGGTCTCCACTTTGTGATAGACATTCGTTCAAATGTGGACAGAAAACAGAGCCAAAGACTTATAGTTTTGTTGGATAAGAAAGCCAAACGATTCTCCCTGCACATCACAGCCACACAGCCTGAAGATTCAGCCATCTACTTCTGTGCAGCAAGCA

Amino-acid sequence (V-REGION)

93 aa
GEKVEQHESTLSVREGDSAVINCTYTDTASSYFPWYKQEAGKGLHFVIDIRSNVDRKQSQRLIVLLDKKAKRFSLHITATQPEDSAIYFCAAS

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (MOUSE-VL6UUQGIJ). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
TRAV10*01 IMGT IMGT

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
MT646511.1 NCBI accession ncbi_nucleotide

External records i

NCBI nucleotide: link IMGT: TRAV10*01

Literature references 17 total · 17 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
22792299 Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets. name mentioned* literature_supp
27460926 Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq. name mentioned* literature_supp
31237075 Comparative analysis of CDR3 regions in paired human αβ CD8 T cells. name mentioned* literature_supp
32868763 Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells. name mentioned* literature_supp
36408799 SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells. name mentioned* literature_supp
37287989 Targeting KRASG12V mutations with HLA class II-restricted TCR for the immunotherapy in solid tumors. name mentioned* literature_supp
38762584 Invariant γδTCR natural killer-like effector T cells in the naked mole-rat. name mentioned* literature_supp
38871688 Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas. name mentioned* literature_supp
38954022 Identification and validation of tumor-specific T cell receptors from tumor infiltrating lymphocytes using tumor organoid co-cultures. name mentioned* literature_supp
39421738 scRNA+TCR-seq reveals the pivotal role of dual receptor T lymphocytes in the pathogenesis of Kawasaki disease and during IVIG treatment. name mentioned* literature_supp
39507623 Development and characterization of human T-cell receptor (TCR) alpha and beta clones' library as biological standards and resources for TCR sequencing and engineering. name mentioned* literature_supp
40165973 T-cell receptors identified by a personalized antigen-agnostic screening approach target shared neoantigen KRAS Q61H. name mentioned* literature_supp
40664667 High-resolution mapping of single cells in spatial context. name mentioned* literature_supp
40866291 Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer. name mentioned* literature_supp
40877317 Molecular basis of potent antiviral HLA-C-restricted CD8+ T cell response to an immunodominant SARS-CoV-2 nucleocapsid epitope. name mentioned* literature_supp
42125653 N-terminal pyroglutamylation of an HLA-A24-restricted immunodominant epitope enhances SARS-CoV-2-specific T-cell responses. name mentioned* literature_supp
42129543 One-step generation of T-cell receptor knock-in mice in the TCRβ locus. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACACTGTTTCCTAGGCACCTGCAGCCTATCCTCAAACT IMGT MOUSE-R6B3PS

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGAAGACATCCCTTCACACTGTATTCCTATTCTTGTGGCTGTGGATGGACTGGGAGAGCCAT 52 + 11 nt IMGT MOUSE-LITG27

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/MOUSE-VL6UUQGIJ/similar?min_identity=0.95&kind=nt.