AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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ORANGBOR-V5PEOXKEG

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesPongo pygmaeus LocusTRA TypeV FunctionalTrue Length276 nt

TRAV26-2*01: a Pongo pygmaeus TRA V allele sequence, 276 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesPongo pygmaeus (NCBITAXON:9600)
Locus / typeTRA / V
Functional iTrue
Length276 nt
Protein UID iORANGBOR-VP-X546ET (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

276 nt
GATGCTAAGACCACACAGCCAAATTCAATGGAGAGTAATGAAGAACAGCCTGTTCACTTGCCTTGTAACCACTCCACAATCAGTGGAACTGATTACATACATTGGTACCGACAGCTTCCCTCCCAGGGTCCAGAGTACGTGATTCATGGTCTTACAAGCAATGTGAACAACAGAATGGCCTCTCTGACAATCGCTGAAGACAGAAAGTCCAGTACCTTGATCCTGCACTGTGCTACCTTGAGAGATGCTGCTGTGTACTACTGCATCTTGAGAGAC

Amino-acid sequence (V-REGION)

92 aa
DAKTTQPNSMESNEEQPVHLPCNHSTISGTDYIHWYRQLPSQGPEYVIHGLTSNVNNRMASLTIAEDRKSSTLILHCATLRDAAVYYCILRD

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (ORANGBOR-V5PEOXKEG). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
TRAV26-2*01 IMGT IMGT

External records i

IMGT: TRAV26-2*01

Literature references 16 total · 1 sequence-in-paper · 15 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
40205052 Complete sequencing of ape genomes. sequence in paper literature_supp
19139173 Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition. name mentioned* literature_supp
22792299 Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets. name mentioned* literature_supp
30152754 Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity. name mentioned* literature_supp
31237075 Comparative analysis of CDR3 regions in paired human αβ CD8 T cells. name mentioned* literature_supp
32040512 Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering. name mentioned* literature_supp
35436998 pmTR database: population matched (pm) germline allelic variants of T-cell receptor (TR) loci. name mentioned* literature_supp
36408799 SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells. name mentioned* literature_supp
37287989 Targeting KRASG12V mutations with HLA class II-restricted TCR for the immunotherapy in solid tumors. name mentioned* literature_supp
38871688 Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas. name mentioned* literature_supp
39421738 scRNA+TCR-seq reveals the pivotal role of dual receptor T lymphocytes in the pathogenesis of Kawasaki disease and during IVIG treatment. name mentioned* literature_supp
40664667 High-resolution mapping of single cells in spatial context. name mentioned* literature_supp
40866291 Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer. name mentioned* literature_supp
41306962 Promiscuous class II-binding SARS-CoV-2-nuc derived vaccine-peptide induced extensive conventional, innate and unconventional T cell responses. name mentioned* literature_supp
41766885 Correction: Promiscuous class II-binding SARS-CoV-2-nuc derived vaccine-peptide induced extensive conventional, innate and unconventional T cell responses. name mentioned* literature_supp
42125653 N-terminal pyroglutamylation of an HLA-A24-restricted immunodominant epitope enhances SARS-CoV-2-specific T-cell responses. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGGGACAGATGGGGCTGCAGCTGTGCAATATCTC IMGT ORANGBOR-RVNXG6

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGAAGTTGGTGACAAGCATTACTGTACTCCTATCTTTGGGTATTACGGGT 40 + 11 nt IMGT ORANGBOR-LGTOHN

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/ORANGBOR-V5PEOXKEG/similar?min_identity=0.95&kind=nt.