AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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ORANGBOR-VZJSN754I

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesPongo pygmaeus LocusTRB TypeV FunctionalTrue Length287 nt

TRBV19*02: a Pongo pygmaeus TRB V allele sequence, 287 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesPongo pygmaeus (NCBITAXON:9600)
Locus / typeTRB / V
Functional iTrue
Length287 nt
Protein UID iORANGBOR-VP-SS7VGS (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

287 nt
GATGGTGGAATCACTCAGTCCCCACAGTACCTGTTCAGAAAGGAAGGACAGAATGTGACCCTGAGTTGTGAACAGAATTTGAACCACGATGCCATGTACTGGTACCGACAGGACCCAGGGCAAGGGCTGAGATTGATCTACTACTCAGAGATAGTAAATGACTTTCAGAAAGGAGACATAGCTGAAGGGTACAGCGTCTCTCGGGAGAAGAAGGAATCCTTTCCTCTCACTGTGACATCGGCCCAAAAGAACCCGACAGCTTTCTATCTCTGTGCCAGTAGTATAGA

Amino-acid sequence (V-REGION)

95 aa
DGGITQSPQYLFRKEGQNVTLSCEQNLNHDAMYWYRQDPGQGLRLIYYSEIVNDFQKGDIAEGYSVSREKKESFPLTVTSAQKNPTAFYLCASSI

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (ORANGBOR-VZJSN754I). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
TRBV19*02 IMGT IMGT

External records i

IMGT: TRBV19*02

Literature references 9 total · 1 sequence-in-paper · 8 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
40205052 Complete sequencing of ape genomes. sequence in paper literature_supp
22792299 Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets. name mentioned* literature_supp
26962778 High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire. name mentioned* literature_supp
31237075 Comparative analysis of CDR3 regions in paired human αβ CD8 T cells. name mentioned* literature_supp
36408799 SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells. name mentioned* literature_supp
36923729 Cross-reactivity influences changes in human influenza A virus and Epstein Barr virus specific CD8 memory T cell receptor alpha and beta repertoires between young and old. name mentioned* literature_supp
38615042 Deep learning predictions of TCR-epitope interactions reveal epitope-specific chains in dual alpha T cells. name mentioned* literature_supp
39472557 Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes. name mentioned* literature_supp
40186144 scTCR-seq and HTS reveal a special novel TRBD2-TRBJ1 rearrangement in mammalian TRB CDR3 repertoire. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGAAGCACTGATGTCACCTCTCTGTGCATAAATG IMGT ORANGBOR-RWWSJR

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGAGCAACCAGGTGCTCTGCTGTGTGGTCCTTTGTCTCCTCGGAGCAAACACCGTG 49 + 8 nt IMGT ORANGBOR-LPNOVP

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/ORANGBOR-VZJSN754I/similar?min_identity=0.95&kind=nt.