AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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ORANGSUM-V5CKN35JJ

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesPongo abelii LocusTRA TypeV FunctionalTrue Length286 nt

TRAV3*01: a Pongo abelii TRA V allele sequence, 286 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesPongo abelii (NCBITAXON:9601)
Locus / typeTRA / V
Functional iTrue
Length286 nt
Protein UID iORANGSUM-VP-PXRMDF (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

286 nt
GCTCAGTCAGTGGCTCAGCCGGAAGATGAGGTCACGGTCGCTGAAGGGAATCCTCTGACTGTGAAATGCACCTATTCAGTCTCTGGAAACCCTTATCTTTTTTGGTATATTCAATACCCCAATGAAGGCCTCCAGTTCCTTCTGAAATACATCACAGGGGACAACCTGGTTAAAGGCAGCTATGGCTTTGAAGCTGAATTTAACAAGAGCCAAACCTCCTTCCACCTGAAGAAACCATCTGCCCTTGTGAGCGACTCCGCTTTGTACTTCTGTGCTGTGAGAGACA

Amino-acid sequence (V-REGION)

95 aa
AQSVAQPEDEVTVAEGNPLTVKCTYSVSGNPYLFWYIQYPNEGLQFLLKYITGDNLVKGSYGFEAEFNKSQTSFHLKKPSALVSDSALYFCAVRD

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (ORANGSUM-V5CKN35JJ). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
TRAV3*01 IMGT IMGT

External records i

IMGT: TRAV3*01

Literature references 18 total · 1 sequence-in-paper · 17 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
40205052 Complete sequencing of ape genomes. sequence in paper literature_supp
22792299 Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets. name mentioned* literature_supp
31237075 Comparative analysis of CDR3 regions in paired human αβ CD8 T cells. name mentioned* literature_supp
32040512 Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering. name mentioned* literature_supp
35436998 pmTR database: population matched (pm) germline allelic variants of T-cell receptor (TR) loci. name mentioned* literature_supp
36408799 SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells. name mentioned* literature_supp
36923729 Cross-reactivity influences changes in human influenza A virus and Epstein Barr virus specific CD8 memory T cell receptor alpha and beta repertoires between young and old. name mentioned* literature_supp
37287989 Targeting KRASG12V mutations with HLA class II-restricted TCR for the immunotherapy in solid tumors. name mentioned* literature_supp
38762584 Invariant γδTCR natural killer-like effector T cells in the naked mole-rat. name mentioned* literature_supp
38871688 Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas. name mentioned* literature_supp
38954022 Identification and validation of tumor-specific T cell receptors from tumor infiltrating lymphocytes using tumor organoid co-cultures. name mentioned* literature_supp
39421738 scRNA+TCR-seq reveals the pivotal role of dual receptor T lymphocytes in the pathogenesis of Kawasaki disease and during IVIG treatment. name mentioned* literature_supp
39472557 Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes. name mentioned* literature_supp
40664667 High-resolution mapping of single cells in spatial context. name mentioned* literature_supp
40775219 Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target. name mentioned* literature_supp
40866291 Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer. name mentioned* literature_supp
40877317 Molecular basis of potent antiviral HLA-C-restricted CD8+ T cell response to an immunodominant SARS-CoV-2 nucleocapsid epitope. name mentioned* literature_supp
42125653 N-terminal pyroglutamylation of an HLA-A24-restricted immunodominant epitope enhances SARS-CoV-2-specific T-cell responses. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACACTGATAGGGGCTGCAGGGGGAGCAGAACACAAACT IMGT ORANGSUM-R7GN3H

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGCCTCTGCACGCCTCTCGACGCTTGCGATGCTCTTCACATTGAGTGGGCTGAGA 46 + 11 nt IMGT ORANGSUM-LIE7NR

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/ORANGSUM-V5CKN35JJ/similar?min_identity=0.95&kind=nt.