ORANGSUM-VCV7CFBG2

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesPongo abelii LocusTRB TypeV FunctionalTrue Length290 nt

TRBV7-2*02: a Pongo abelii TRB V allele sequence, 290 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

Species	Pongo abelii (NCBITAXON:9601)
Locus / type	TRB / V
Functional i	True
Length	290 nt
Protein UID i	ORANGSUM-VP-QRWAMC (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

290 nt

GGAGCTGGAGTCTCCCAGTCCCCCAGTAACAAGGTCACAGAGAAGGGAAAGGATGTAGAGCTCAGGTGTGATCCAATTTCGGGTCATACTGCCCTTTACTGGTACGGACAGAGCCTGGGGCAGGGCCTGGAGTTTTTAATTTACTTCCAAGGCAACAGTGCACCAGACGAATCAGGGCTGCCCAGTGATCGCTTCTATGCAGAGAGGTCTGGGGGATCCATCTCCACTCTGAAGATCCAGCGTACACAGCAGGAGGACTCGGCCGTGTATCTCTGTGCCAGCAGCTTAGC

Amino-acid sequence (V-REGION)

96 aa

GAGVSQSPSNKVTEKGKDVELRCDPISGHTALYWYGQSLGQGLEFLIYFQGNSAPDESGLPSDRFYAERSGGSISTLKIQRTQQEDSAVYLCASSL

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (ORANGSUM-VCV7CFBG2). None is canonical; they are labels, and the UID is the key.

Name	Scheme	Source(s)
TRBV7-2*02	IMGT	IMGT

External records i

IMGT: TRBV7-2*02

Literature references 22 total · 1 sequence-in-paper · 21 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMID	Title	Evidence	Source
40205052	Complete sequencing of ape genomes.	sequence in paper	literature_supp
22792299	Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets.	name mentioned^*	literature_supp
26147596	Structure of Staphylococcal Enterotoxin E in Complex with TCR Defines the Role of TCR Loop Positioning in Superantigen Recognition.	name mentioned^*	literature_supp
26962778	High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire.	name mentioned^*	literature_supp
30152754	Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity.	name mentioned^*	literature_supp
31237075	Comparative analysis of CDR3 regions in paired human αβ CD8 T cells.	name mentioned^*	literature_supp
34316355	iCAT: diagnostic assessment tool of immunological history using high-throughput T-cell receptor sequencing.	name mentioned^*	literature_supp
34991709	T cell receptor beta germline variability is revealed by inference from repertoire data.	name mentioned^*	literature_supp
35436998	pmTR database: population matched (pm) germline allelic variants of T-cell receptor (TR) loci.	name mentioned^*	literature_supp
36408799	SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells.	name mentioned^*	literature_supp
36923729	Cross-reactivity influences changes in human influenza A virus and Epstein Barr virus specific CD8 memory T cell receptor alpha and beta repertoires between young and old.	name mentioned^*	literature_supp
37468623	A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection.	name mentioned^*	literature_supp
38615042	Deep learning predictions of TCR-epitope interactions reveal epitope-specific chains in dual alpha T cells.	name mentioned^*	literature_supp
38871688	Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas.	name mentioned^*	literature_supp
39421738	scRNA+TCR-seq reveals the pivotal role of dual receptor T lymphocytes in the pathogenesis of Kawasaki disease and during IVIG treatment.	name mentioned^*	literature_supp
39472557	Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes.	name mentioned^*	literature_supp
39507623	Development and characterization of human T-cell receptor (TCR) alpha and beta clones' library as biological standards and resources for TCR sequencing and engineering.	name mentioned^*	literature_supp
40664667	High-resolution mapping of single cells in spatial context.	name mentioned^*	literature_supp
40877317	Molecular basis of potent antiviral HLA-C-restricted CD8+ T cell response to an immunodominant SARS-CoV-2 nucleocapsid epitope.	name mentioned^*	literature_supp
41306962	Promiscuous class II-binding SARS-CoV-2-nuc derived vaccine-peptide induced extensive conventional, innate and unconventional T cell responses.	name mentioned^*	literature_supp
41766885	Correction: Promiscuous class II-binding SARS-CoV-2-nuc derived vaccine-peptide induced extensive conventional, innate and unconventional T cell responses.	name mentioned^*	literature_supp
42125653	N-terminal pyroglutamylation of an HLA-A24-restricted immunodominant epitope enhances SARS-CoV-2-specific T-cell responses.	name mentioned^*	literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

Part	Sequence	Source	RSS UID
v_rs	CACAGCGTGGCCCAGTCGCCTCCTTCCTGCTCATAAACC	IMGT	ORANGSUM-RQA4WE

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)	Split	Source	Leader UID
ATGGGCACCAGGTTCCTCTGCTGGGCGGCCCTCTGTCTCCTGGGGGCAGATCACACA	49 + 8 nt	IMGT	ORANGSUM-LD7MJL

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/ORANGSUM-VCV7CFBG2/similar?min_identity=0.95&kind=nt.

API: JSON · AIRR AlleleDescription · aliases