AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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ORANGSUM-VIAQNRMHT

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesPongo abelii LocusTRB TypeV FunctionalNone Length290 nt

TRBV12-1*01: a Pongo abelii TRB V allele sequence, 290 nt, not recorded. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesPongo abelii (NCBITAXON:9601)
Locus / typeTRB / V
Functional iNone
Length290 nt
Protein UID iORANGSUM-VP-DP2AS5 (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

290 nt
GATGTTGGCATTATCCAGTCGCCCAGGCACAAAGTGACAGAGATGGGACAATCAATAACTCTGAGATGCGAACCTATTTCAGGCCACAGTGATCTTCTCTGGTACAGACAGACCTTGGTGCAGGGACTGGAATTGCTGAATTACTTCCGCAGCCGGACCCTCGTAGATGACTCAGGGATGCCCAAGGATCAATTCTCAGCATAGATGCCTGATGTATCATTCTCCACTCTGAGGATCCAGCCCACGGAACCCAGGGACTCGGGCCTGTATTTCTGTGCCAGCAGCTTTGC

Amino-acid sequence (V-REGION)

96 aa
DVGIIQSPRHKVTEMGQSITLRCEPISGHSDLLWYRQTLVQGLELLNYFRSRTLVDDSGMPKDQFSA*MPDVSFSTLRIQPTEPRDSGLYFCASSF

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (ORANGSUM-VIAQNRMHT). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
TRBV12-1*01 IMGT IMGT

External records i

IMGT: TRBV12-1*01

Literature references 9 total · 9 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
32868763 Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells. name mentioned* literature_supp
34845983 TCR meta-clonotypes for biomarker discovery with tcrdist3 enabled identification of public, HLA-restricted clusters of SARS-CoV-2 TCRs. name mentioned* literature_supp
35436998 pmTR database: population matched (pm) germline allelic variants of T-cell receptor (TR) loci. name mentioned* literature_supp
38762584 Invariant γδTCR natural killer-like effector T cells in the naked mole-rat. name mentioned* literature_supp
38871688 Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas. name mentioned* literature_supp
39133650 Expansion of the HSV-2-specific T cell repertoire in skin after immunotherapeutic HSV-2 vaccine. name mentioned* literature_supp
39421738 scRNA+TCR-seq reveals the pivotal role of dual receptor T lymphocytes in the pathogenesis of Kawasaki disease and during IVIG treatment. name mentioned* literature_supp
41096855 A High-Throughput Sequencing Strategy for Clinical Repertoire Profiling of T Cell Receptor Beta Chain: Development and Reference Values Across Healthy Adults, Paediatrics, and Cord Blood Units. name mentioned* literature_supp
41941497 Pigs lacking Natural Killer T cells have altered cellular responses to influenza. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGCACTGTAGAATCTCCCCATCTCTGTGCAGAAACC IMGT ORANGSUM-RISLCX

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGGCTCTTGGACCCTCTGTGTGTCCCTTTATATCCTGGTAGTGACACACACA 46 + 8 nt IMGT ORANGSUM-LHQGI2

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/ORANGSUM-VIAQNRMHT/similar?min_identity=0.95&kind=nt.