AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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ORANGSUM-VNLWCJKMF

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesPongo abelii LocusIGH TypeV FunctionalNone Length303 nt

IGHV3-64*03: a Pongo abelii IGH V allele sequence, 303 nt, not recorded. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesPongo abelii (NCBITAXON:9601)
Locus / typeIGH / V
Functional iNone
Length303 nt
Protein UID iORANGSUM-VP-4R2MSA (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

303 nt
GAGGTGCTTCTGGTGGAGTCTTTGGGAGGCTTGTTATATCCTGGGGGTCCCTGAGACTTTCTTTTGCAGCCTCTGGATTCACCTTTAGTACCTTTAGTAGGTACTGGATGAGCTGCCGTCCATCAAGCTCCTGGGAAAGGGCTGCAGTAGGTCTCATTTATGAGTTGTTGTGTAGGTAGCACAAACTATGCAGACTCTGTGAAGGGTCGATTCACCGTCTCCAGAGATGATGCCAAGAAATCACTGTATCTGCAAATGAACAGCGTGAGAGCCTAGGATAGGTCTGTGTATTACTGTAGTGGC

Amino-acid sequence (V-REGION)

101 aa
EVLLVESLGGLLYPGGP*DFLLQPLDSPLVPLVGTG*AAVHQAPGKGLQ*VSFMSCCVGSTNYADSVKGRFTVSRDDAKKSLYLQMNSVRA*DRSVYYCSG

Translated here from the nucleotide sequence; no source published a protein for this allele. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (ORANGSUM-VNLWCJKMF). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV3-64*03 IMGT IMGT

External records i

IMGT: IGHV3-64*03

Literature references 8 total · 8 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
31839985 More than one antibody of individual B cells revealed by single-cell immune profiling. name mentioned* literature_supp
34785098 Landscapes and dynamic diversifications of B-cell receptor repertoires in COVID-19 patients. name mentioned* literature_supp
35545447 Gene prediction in the immunoglobulin loci. name mentioned* literature_supp
36328595 Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing. name mentioned* literature_supp
39840032 An allelic atlas of immunoglobulin heavy chain variable regions reveals antibody binding epitope preference resilient to SARS-CoV-2 mutation escape. name mentioned* literature_supp
40664667 High-resolution mapping of single cells in spatial context. name mentioned* literature_supp
41617721 Refined phenotyping of vaccine responses reveals transcriptomic determinants of neutralizing antibody heterogeneity. name mentioned* literature_supp
42078068 B-cell immune repertoire analysis of autoimmune neurological syndromes with anti-GAD65 antibodies. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGAGTTTGGGCTGAGCTGGGTTTTCCTTGTTGCTAATGTAAAAGGTGTCCAGTGT 46 + 11 nt IMGT ORANGSUM-L63TQN

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/ORANGSUM-VNLWCJKMF/similar?min_identity=0.95&kind=nt.