AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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ORANGSUM-VQ3GT66A7

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesPongo abelii LocusIGH TypeV FunctionalNone Length296 nt
SpeciesPongo abelii (NCBITAXON:9601)
Locus / typeIGH / V
Functional iNone
Length296 nt
Protein UID iORANGSUM-VP-FUMMNW (shared by alleles with the same V-REGION amino-acid sequence)

Allele names i

Every name below denotes this exact sequence (ORANGSUM-VQ3GT66A7). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV1-80*01 IMGT IMGT

External records i

IMGT: IGHV1-80*01

Literature references 8 total · 1 sequence-in-paper · 7 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
40205052 Complete sequencing of ape genomes. sequence in paper literature_supp
29545810 Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification. name mentioned* literature_supp
36473496 Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination. name mentioned* literature_supp
36604758 Bacteroides-derived isovaleric acid enhances mucosal immunity by facilitating intestinal IgA response in broilers. name mentioned* literature_supp
37938344 Role of affinity in plasma cell development in the germinal center light zone. name mentioned* literature_supp
39127707 Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonally and functionally restricted. name mentioned* literature_supp
39698082 Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten. name mentioned* literature_supp
41410768 Convergent mutation trajectories convert functional self-tolerance in IGHV4-34 B cells to genetic tolerance encoded in the antibody. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGTGAGAAACCACATCCTCAGAGTGTCAGAAACC IMGT ORANGSUM-REXJRY

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGACTGGACCTGGAGGGTCTTCTGCTTGCTGGCTGTAGCTCCAGGTGCTCACTCC 46 + 11 nt IMGT ORANGSUM-L5S3O6

Find similar alleles

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/ORANGSUM-VQ3GT66A7/similar?min_identity=0.95&kind=nt.

Coding sequence (nt)

296 nt
CAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAGGCCTGGGGCCTCAGTGAAGGTTTCCTGCAAGGCTTCTGGTTACACCTTCACCAGCTGCTATATGTACTGGGTGCAACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAGTAATCAACCCTAGTGATGGTAGCACAAGCTACGCACAGAAGTTCCAGGGCAGAGTCACCATGACCAGGGACACATCCACAAGCACAGTCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTATGCAAGAGA

Amino-acid sequence (V-REGION)

98 aa
QVQLVQSGAEVKRPGASVKVSCKASGYTFTSCYMYWVQQAPGQGLEWMGVINPSDGSTSYAQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYYAR

Published by the source, and consistent with the nucleotide sequence above. i