AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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ORANGSUM-VTRVCBMRU

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesPongo abelii LocusIGK TypeV FunctionalTrue Length287 nt

IGKV1-17*02: a Pongo abelii IGK V allele sequence, 287 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesPongo abelii (NCBITAXON:9601)
Locus / typeIGK / V
Functional iTrue
Length287 nt
Protein UID iORANGSUM-VP-KWGFTV (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

287 nt
GACATCCAGATGACCCAGTCTCCATCTTCCGTGTCTGCATCTGTAGGAGACAGAGTCACCATCACTTGTCGGGCAAGTCAGAGCATTAGCAGTTATTTAGCCTGGTATCAGCAAAAACCAGGGAAAGCCCCTAAGCCCCTGATCTATGCTGCATCCAATTTGCAAAGTGGGGTTCCCTCGAGGTTCAGCGGCAGTGGATCTGGGACAGAATTCACTCTCACCATCAGCAGCCTGCAGCCTGAAGATTTTGCAACCTATTACTGTCAACAATATAAGAGTGACCCTCC

Amino-acid sequence (V-REGION)

95 aa
DIQMTQSPSSVSASVGDRVTITCRASQSISSYLAWYQQKPGKAPKPLIYAASNLQSGVPSRFSGSGSGTEFTLTISSLQPEDFATYYCQQYKSDP

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (ORANGSUM-VTRVCBMRU). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGKV1-17*02 IMGT IMGT

External records i

IMGT: IGKV1-17*02

Literature references 7 total · 1 sequence-in-paper · 6 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
40205052 Complete sequencing of ape genomes. sequence in paper literature_supp
31839985 More than one antibody of individual B cells revealed by single-cell immune profiling. name mentioned* literature_supp
34587480 Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses. name mentioned* literature_supp
35447092 Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins. name mentioned* literature_supp
35776090 Antibody evolution to SARS-CoV-2 after single-dose Ad26.COV2.S vaccine in humans. name mentioned* literature_supp
36328595 Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing. name mentioned* literature_supp
40664667 High-resolution mapping of single cells in spatial context. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGTTACACACCCGAACAAAAACC IMGT ORANGSUM-RCX5GO

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGACATGAGGGTTCCTGCTCAGCTCCTGGGGCTCCTGCTGCTCTGGCTCCCAGGTGCCAGAGGT 55 + 11 nt IMGT ORANGSUM-LSBOMV

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/ORANGSUM-VTRVCBMRU/similar?min_identity=0.95&kind=nt.