AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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PLATYPUS-VN45UQH42

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesOrnithorhynchus anatinus LocusIGH TypeV FunctionalNone Length295 nt

IGHV1-15*01: a Ornithorhynchus anatinus IGH V allele sequence, 295 nt, not recorded. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesOrnithorhynchus anatinus (NCBITAXON:9258)
Locus / typeIGH / V
Functional iNone
Length295 nt
Protein UID iPLATYPUS-VP-MHH5XV (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

295 nt
GATGTCCAGCTGGTGGAGTCCAGGGAGACGTAAGACAGCCCGGGGGTTCTCTGCGTCTCTCCTGTAAAGCCTCCGGATTCACCTTTAGCAGCCATGGGATGCACTGGGTCCGCCAGGCTCCAGGGACGAGGCTGGAATGGGTGGCAGCTATAAATAGCAAAGGGGACTGGACAAGCTATCGAGACTCTGTGAAAGGCCGATTCACCATCTCCAGGGAGAATGCCAACAGCCTGCTGCATCTGCAAATGAACAGCCTGAAAACTGAGGACACAGCCCTCTATTACTGTACGAGAGA

Amino-acid sequence (V-REGION)

97 aa
CPAGGVQGDVRQPGGSLRLSCKASGFTFSSHGMHWVRQAPGTRLEWVAAINSKGDWTSYRDSVKGRFTISRENANSLLHLQMNSLKTEDTALYYCTR

Translated here from the nucleotide sequence; no source published a protein for this allele. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (PLATYPUS-VN45UQH42). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV1-15*01 IMGT IMGT

External records i

IMGT: IGHV1-15*01

Literature references 12 total · 12 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
29545810 Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification. name mentioned* literature_supp
32326443 Exploration and Modulation of Antibody Fragment Biophysical Properties by Replacing the Framework Region Sequences. name mentioned* literature_supp
34813501 B cell receptor isotypes differentially associate with cell signaling, kinetics, and outcome in chronic lymphocytic leukemia. name mentioned* literature_supp
36473496 Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination. name mentioned* literature_supp
36604758 Bacteroides-derived isovaleric acid enhances mucosal immunity by facilitating intestinal IgA response in broilers. name mentioned* literature_supp
39127707 Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonally and functionally restricted. name mentioned* literature_supp
39698082 Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten. name mentioned* literature_supp
40338637 Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein. name mentioned* literature_supp
41021799 Molecular divergence and convergence of mammalian antibody responses to the influenza virus hemagglutinin stem. name mentioned* literature_supp
41410768 Convergent mutation trajectories convert functional self-tolerance in IGHV4-34 B cells to genetic tolerance encoded in the antibody. name mentioned* literature_supp
41873331 Porcine influenza mAbs to H3, H5, and H7 hemagglutinins recognize H3 egg adapted site and target the HA stem. name mentioned* literature_supp
41941497 Pigs lacking Natural Killer T cells have altered cellular responses to influenza. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACATTGCAGGACCATGAGTGTGAGCCCAGACACATACC IMGT PLATYPUS-RHVJDJ

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGCAGTCTGCCCTCAATCTGCTTTCCATCCTCATCCTGCTCCAAGGTGTCCAGGGT 46 + 11 nt IMGT PLATYPUS-LR77ZY

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/PLATYPUS-VN45UQH42/similar?min_identity=0.95&kind=nt.