AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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RABBIT-V2OF7VCAT

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesOryctolagus cuniculus LocusTRB TypeV FunctionalTrue Length285 nt

TRBV6-8*01: a Oryctolagus cuniculus TRB V allele sequence, 285 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesOryctolagus cuniculus (NCBITAXON:9986)
Locus / typeTRB / V
Functional iTrue
Length285 nt
Protein UID iRABBIT-VP-QAEBJ2 (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

285 nt
AATGCTGGTGTCACTCAGAGCCCCAAATTCCAGGTCCTAAAGACAGGACAGAGCCTGACCTTGAAATGTACCCAGGATATGAGCCATAACTACATGTACTGGTACCGCCAGGACCCAGGGCTGGGGCTGAAGCTCATCTATTACTCAGTTGGCCGTGACACCGATGCGAAAGGAGAGGTCTCCGATGGGTACAACGTGTCCAGACCAAGCACAGAGGAGTTCCCCCTCATGCTGCTGTCAGCTGTCCCCTCACAGACATCTGTGTACTTCTGTGCCAGCAGTTAC

Amino-acid sequence (V-REGION)

95 aa
NAGVTQSPKFQVLKTGQSLTLKCTQDMSHNYMYWYRQDPGLGLKLIYYSVGRDTDAKGEVSDGYNVSRPSTEEFPLMLLSAVPSQTSVYFCASSY

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (RABBIT-V2OF7VCAT). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
TRBV6-8*01 IMGT IMGT

External records i

IMGT: TRBV6-8*01

Literature references 6 total · 6 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
36408799 SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells. name mentioned* literature_supp
38336680 NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route. name mentioned* literature_supp
39133650 Expansion of the HSV-2-specific T cell repertoire in skin after immunotherapeutic HSV-2 vaccine. name mentioned* literature_supp
39421738 scRNA+TCR-seq reveals the pivotal role of dual receptor T lymphocytes in the pathogenesis of Kawasaki disease and during IVIG treatment. name mentioned* literature_supp
40866291 Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer. name mentioned* literature_supp
41424382 Identification of Sjögren's disease-associated T cell receptor motifs through deep sequencing. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGCCCTGCACAGACACCTGCTCTCTGCACATAAACC IMGT RABBIT-RPLU5P

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGAGTGTGGGTCCCCTGAGCTGTGTGGTCCTTTGTCTCCTGCTGGCAGGTCCAGCG 49 + 8 nt IMGT RABBIT-LJM6UO

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/RABBIT-V2OF7VCAT/similar?min_identity=0.95&kind=nt.