AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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RABBIT-VVK3YRF4E

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesOryctolagus cuniculus LocusTRB TypeV FunctionalTrue Length284 nt

TRBV6-3*01: a Oryctolagus cuniculus TRB V allele sequence, 284 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesOryctolagus cuniculus (NCBITAXON:9986)
Locus / typeTRB / V
Functional iTrue
Length284 nt
Protein UID iRABBIT-VP-AC5EYW (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

284 nt
AATGCTGGTGTCACTCAGAGCCCCAAGTTCCAGGTCCTAAAGACAGGACAGAGCCTGACCTTGAGATGTGCCCAGGATATGAACTATGACTACATGTGCTGGTACCGCCAGGACCCAGGGCTGGGGCTGAAGCTCATTTATTACTCAGCTGTCCAAGGCACCCATGAGAAAGGAGATGATCCCGACGGGTACAACGCGTCTAGACCAAGCACAAAGGAGTTCCCCCTCACGCTGCTGTCAGCTGTCCCCTCGCAGACATCTGTGTACTTGTGTGCAGCAATTAC

Amino-acid sequence (V-REGION)

94 aa
NAGVTQSPKFQVLKTGQSLTLRCAQDMNYDYMCWYRQDPGLGLKLIYYSAVQGTHEKGDDPDGYNASRPSTKEFPLTLLSAVPSQTSVYLCAAI

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (RABBIT-VVK3YRF4E). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
TRBV6-3*01 IMGT IMGT

External records i

IMGT: TRBV6-3*01

Literature references 13 total · 13 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
23995877 IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling. name mentioned* literature_supp
26962778 High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire. name mentioned* literature_supp
34343164 Using de novo assembly to identify structural variation of eight complex immune system gene regions. name mentioned* literature_supp
34991709 T cell receptor beta germline variability is revealed by inference from repertoire data. name mentioned* literature_supp
36408799 SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells. name mentioned* literature_supp
36603583 Improved predictions of antigen presentation and TCR recognition with MixMHCpred2.2 and PRIME2.0 reveal potent SARS-CoV-2 CD8+ T-cell epitopes. name mentioned* literature_supp
36923729 Cross-reactivity influences changes in human influenza A virus and Epstein Barr virus specific CD8 memory T cell receptor alpha and beta repertoires between young and old. name mentioned* literature_supp
38871688 Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas. name mentioned* literature_supp
39472557 Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes. name mentioned* literature_supp
40186144 scTCR-seq and HTS reveal a special novel TRBD2-TRBJ1 rearrangement in mammalian TRB CDR3 repertoire. name mentioned* literature_supp
40775219 Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target. name mentioned* literature_supp
41150899 Large-Scale T-cell Receptor Repertoire Profiling Unveils Tumor-Specific Signals for Diagnosing Indeterminate Pulmonary Nodules. name mentioned* literature_supp
41424382 Identification of Sjögren's disease-associated T cell receptor motifs through deep sequencing. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGCCCTGCACAGCCACCTGCTGTCTGCACATAAACC IMGT RABBIT-RMESE4

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGAGTGTGGGTCCCCTGAGCTGTGTGGTCCTTTGTCTCCTGCTGGCAGGTCCAGCC 49 + 8 nt IMGT RABBIT-LHUXUV

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/RABBIT-VVK3YRF4E/similar?min_identity=0.95&kind=nt.