AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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RAT-VAT2EJARP

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesRattus norvegicus LocusIGH TypeV FunctionalNone Length299 nt

IGHV5-2*01: a Rattus norvegicus IGH V allele sequence, 299 nt, not recorded. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesRattus norvegicus (NCBITAXON:10116)
Locus / typeIGH / V
Functional iNone
Length299 nt
Protein UID iRAT-VP-ADTFIP (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

299 nt
GAGGTACAGCTGGTTGAGTCTGGGGGAGGCTTAGTGCAGCCCAGAAGGTCCCTGAAACTCTCCTGTGCAGCCTCTGGATTCACTTTCATTAACTATGGGATAAACTGGGTCCACCAGACTCCAGAAAAGATTCTGGAGTGGGTGGCATATATTAGTCGTGCTAGTAATGACATCTACTATGCAGACACCATGAAGGGCCAATTCACCATCTCCAGAGACAATGCCAAGAACACCCTGTACCTGCAACTAAGCAGTCTGAGGTCTGAGGACACAGCCTTCTTGTATTTCTGTGCAGGAGA

Amino-acid sequence (V-REGION)

99 aa
EVQLVESGGGLVQPRRSLKLSCAASGFTFINYGINWVHQTPEKILEWVAYISRASNDIYYADTMKGQFTISRDNAKNTLYLQLSSLRSEDTAFLYFCAG

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (RAT-VAT2EJARP). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV5-2*01 IMGT IMGT

External records i

IMGT: IGHV5-2*01

Literature references 3 total · 3 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
34813501 B cell receptor isotypes differentially associate with cell signaling, kinetics, and outcome in chronic lymphocytic leukemia. name mentioned* literature_supp
39698082 Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten. name mentioned* literature_supp
41410768 Convergent mutation trajectories convert functional self-tolerance in IGHV4-34 B cells to genetic tolerance encoded in the antibody. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGAGTGAATGTTTCTGTGAGCTCCAACACAGACA IMGT RAT-RXC7IH

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGATTTTGGGCTCTGCTTGGTTTTCCTTGCCCTTATTTTAAAAGGTGTCCAGTGT 46 + 11 nt IMGT RAT-LRNPNQ

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/RAT-VAT2EJARP/similar?min_identity=0.95&kind=nt.