AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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RHESUS-V3OJTAOGS

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMacaca mulatta LocusIGK TypeV FunctionalTrue Length287 nt

IGKV3-40*02, IGKV3-ABF*01_S6676: a Macaca mulatta IGK V allele sequence, 287 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesMacaca mulatta (NCBITAXON:9544)
Locus / typeIGK / V
Functional iTrue
Length287 nt
Protein UID iRHESUS-VP-VJVE2J (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

287 nt
GAAATTGTAATGACGCAGTCTCCAGCCACCCTGTCTTTGTCTCCAGGGGAAACAGCCACCCTCTCCTGCAGGGCCAGTGAGAGTGTTGGCAGCTACTTAGCCTGGTACCAGCAGAAACCTGGGCAGGCTCCCAAGCTCCTTGTCCATAGTGCATACTTCAGGGCCACTGGCATCCCAGACAGGTTCAGTGGCAGCGGGTCTAGGACAGAGTTCACTCTCACCATTAGCAGCCTGGAGCCTGAAGATGTTGGAGTTTATCACTGTCAGCAGTATAATGACTTGCTTCC

Amino-acid sequence (V-REGION)

95 aa
EIVMTQSPATLSLSPGETATLSCRASESVGSYLAWYQQKPGQAPKLLVHSAYFRATGIPDRFSGSGSRTEFTLTISSLEPEDVGVYHCQQYNDLL

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: formerly IGKV3-3*01 (to 2019-03-01);

Allele names i

Every name below denotes this exact sequence (RHESUS-V3OJTAOGS). None is canonical; they are labels, and the UID is the key.

Multiple allele designations. This one sequence is recorded under 2 different allele designations: IGKV3-40*02, IGKV3-ABF*01_S6676. These are identical normalized nucleotide sequences with different attributed names.

NameSchemeSource(s)
IGKV3-F7UZ*07 IgLabel MUSA
IGKV3-TVG6*04 IgLabel OGRDB
IGKV3-40*02 IMGT IMGT
IGKV3-ABF*01_S6676 VRC VRC

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
NW_001099007.1 NCBI accession ncbi_nucleotide

Former IMGT names i

Former nameLast seen in IMGT release
IGKV3-3*012019-03-01

External records i

NCBI nucleotide: link NCBI Gene: NCBIGENE:701244 GenBank: GENBANK:NW_001099007 IMGT: IGKV3-40*02 OGRDB: IGKV3-TVG6*04

Literature references 5 total · 1 sequence-in-paper · 4 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
32866207 Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. sequence in paper literature_supp
28813462 A comprehensive profiling of T- and B-lymphocyte receptor repertoires from a Chinese-origin rhesus macaque by high-throughput sequencing. name mentioned* literature_supp
28899929 Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens. name mentioned* literature_supp
29545810 Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification. name mentioned* literature_supp
41410768 Convergent mutation trajectories convert functional self-tolerance in IGHV4-34 B cells to genetic tolerance encoded in the antibody. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, MUSA, OGRDB, VRC, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGATTCAACAGGAAACAAAAACC IMGT MUSA RHESUS-R2C7CC

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGAAGCCCCAGCACAGCTTCTCTTCCTCCTGCTGCTCTGGATCCCAGATACCGCCGGA 49 + 11 nt IMGT RHESUS-LF2RFU
ATGGAAGCCCCAGCACAGCTTCTCTTCCTCCTGCTGCTCTGGATCCCAGGTATACCGCCGGA 51 + 11 nt MUSA RHESUS-LPFH23
ATGGAAGCCCCAGCACAGCTTCTCTTCCTCCTGCTGCTCTGGATCCCAGGTATACCACTGGA 51 + 11 nt MUSA RHESUS-LVX6MJ

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/RHESUS-V3OJTAOGS/similar?min_identity=0.95&kind=nt.