AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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RHESUS-VCKN4R3V3

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMacaca mulatta LocusIGH TypeV FunctionalFalse Length301 nt
SpeciesMacaca mulatta (NCBITAXON:9544)
Locus / typeIGH / V
Functional iFalse
Length301 nt
Protein UID iRHESUS-VP-JTEM4W (shared by alleles with the same V-REGION amino-acid sequence)

Allele names i

Every name below denotes this exact sequence (RHESUS-VCKN4R3V3). None is canonical; they are labels, and the UID is the key.

Multiple allele designations. This one sequence is recorded under 4 different allele designations: IGHV2-95*02, IGHV2-69*02, LJI.Rh_IGHV2.69.a, IGHV2-AEY-S*02_S4163. These are identical normalized nucleotide sequences with different attributed names.

NameSchemeSource(s)
IGHV2-5KIN*08 IgLabel MUSA
IGHV2-5VX5*11 IgLabel OGRDB
IGHV2-95*02 IMGT IMGT
IGHV2-69*02 KIMDB KIMDB
LJI.Rh_IGHV2.69.a RhGLDB+ RhGLDB+
IGHV2-AEY-S*02_S4163 VRC VRC

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
SBKD01011378.1 NCBI accession ncbi_nucleotide

External records i

NCBI nucleotide: link GenBank: GENBANK:SBKD01011378 IMGT: IGHV2-95*02 OGRDB: IGHV2-5VX5*11

Literature references 5 total · 1 verified · 4 sequence-in-paper i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence.

PMIDTitleEvidenceSource
31080066 verified MUSA
32866207 Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. sequence in paper literature_supp
35419009 Addressing IGHV Gene Structural Diversity Enhances Immunoglobulin Repertoire Analysis: Lessons From Rhesus Macaque. sequence in paper literature_supp
38707998 Maintenance of caecal homeostasis by diverse adaptive immune cells in the rhesus macaque. sequence in paper literature_supp
39068149 Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques. sequence in paper literature_supp

Contributed by IMGT, KIMDB, MUSA, OGRDB, RhGLDB+, VRC, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGAGACACAGCCCCGGGCGCCTCCTGTACAAGAACC IMGT MUSA RHESUS-RIHVVP

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGACACGCTTTGCTACACACTCCTGCTACTGACCGTCCCGTCCTGTGGGTCTTGTCC 48 + 11 nt MUSA RHESUS-LAMHJA
ATGGACACGCTTTGCTACACACTCCTGCTACTGACCGTCCCGTCCTGGTCTTGTCC 46 + 10 nt IMGT RHESUS-LF7UOZ

Find similar alleles

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/RHESUS-VCKN4R3V3/similar?min_identity=0.95&kind=nt.

Coding sequence (nt)

301 nt
CAGGTCACCTTGAAGGAGTCTGGTCCTGCGCTCGTGAAACCCACACAGACCCTCACGCTGACCTGCACCTTCTCTGGGTTCTCAATCAGCACTACTGGAACAGGTGTGGGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAATGGCTTGCAAGCATTTATTGGAATGATAGTAAATACTACAGCACATCGCTGAAGAGCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTTCTGACAATGACCAACATGGACCCTGTGGACACAGCCACATATTACTGTGCACGGGTAC

Amino-acid sequence (V-REGION)

100 aa
QVTLKESGPALVKPTQTLTLTCTFSGFSISTTGTGVGWIRQPPGKALEWLASIYWNDSKYYSTSLKSRLTISKDTSKNQVVLTMTNMDPVDTATYYCARV

Published by the source, and consistent with the nucleotide sequence above. i