AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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RHESUS-VQXJX4EAW

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMacaca mulatta LocusIGK TypeV FunctionalTrue Length287 nt
SpeciesMacaca mulatta (NCBITAXON:9544)
Locus / typeIGK / V
Functional iTrue
Length287 nt
Protein UID iRHESUS-VP-GJ2WSB (shared by alleles with the same V-REGION amino-acid sequence)

Allele names i

Every name below denotes this exact sequence (RHESUS-VQXJX4EAW). None is canonical; they are labels, and the UID is the key.

Multiple allele designations. This one sequence is recorded under 2 different allele designations: IGKV3-10*02, IGKV3-AED-S*01_S4455. These are identical normalized nucleotide sequences with different attributed names.

NameSchemeSource(s)
IGKV3-7Y35*01 IgLabel MUSA
IGKV3-EDGP*03 IgLabel OGRDB
IGKV3-10*02 IMGT IMGT
IGKV3-AED-S*01_S4455 VRC VRC

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
NW_001099007.1 NCBI accession ncbi_nucleotide

Former IMGT names i

Former nameLast seen in IMGT release
IGKV3-9*012019-03-01

External records i

NCBI nucleotide: link NCBI Gene: NCBIGENE:701244 GenBank: GENBANK:NW_001099007 IMGT: IGKV3-10*02 OGRDB: IGKV3-EDGP*03

Literature references 7 total · 2 sequence-in-paper · 5 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
32866207 Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. sequence in paper literature_supp
39068149 Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques. sequence in paper literature_supp
28813462 A comprehensive profiling of T- and B-lymphocyte receptor repertoires from a Chinese-origin rhesus macaque by high-throughput sequencing. name mentioned* literature_supp
37640732 Engaging an HIV vaccine target through the acquisition of low B cell affinity. name mentioned* literature_supp
38707998 Maintenance of caecal homeostasis by diverse adaptive immune cells in the rhesus macaque. name mentioned* literature_supp
39698082 Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten. name mentioned* literature_supp
41410768 Convergent mutation trajectories convert functional self-tolerance in IGHV4-34 B cells to genetic tolerance encoded in the antibody. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, MUSA, OGRDB, VRC, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGATTCAACATGAAACAAAAACC IMGT MUSA RHESUS-RBC5TX

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGAAGCCCCAGCTCGGCTTCTCTGCCTTCTGCTACTCTGGCTCCCAGGTGTACCACCGGA 51 + 11 nt MUSA RHESUS-L7GZ34
ATGGAAGCCCCAGCTCGGCTTCTCTGCCTTCTGCTACTCTGGCTCCCAGGTACCACCGGA 49 + 11 nt IMGT RHESUS-LDW26D

Find similar alleles

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/RHESUS-VQXJX4EAW/similar?min_identity=0.95&kind=nt.

Coding sequence (nt)

287 nt
CAAGTTATATTGACACAGTCTCCAGCCACCCTGTCTTTGTCTCCAGGGGAAAGAGCCACTCTCTCCTGCAGGGCCAGTCAGAGTGTTAGCAGCTACTTAGCCTGGTACCAGCAGAAACCTGGGCAGGCTCCCAGGCTCCTCATCCACAGTGCGTCCAGCAGGGCCACTGGCATCCCAGACAGGTTCAGTGGCAGCGGGTCTGGGACAGAGTTCACCCTCACCATCAGCAGCCTGGAGCCTGAAGATGTTGGAGTTTATCACTGCTATCAGTATTACAGCGGGTACCC

Amino-acid sequence (V-REGION)

95 aa
QVILTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIHSASSRATGIPDRFSGSGSGTEFTLTISSLEPEDVGVYHCYQYYSGY

Published by the source, and consistent with the nucleotide sequence above. i