AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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RHESUS-VSPRNIYKC

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMacaca mulatta LocusIGL TypeV FunctionalTrue Length299 nt

IGLV3-2*01: a Macaca mulatta IGL V allele sequence, 299 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesMacaca mulatta (NCBITAXON:9544)
Locus / typeIGL / V
Functional iTrue
Length299 nt
Protein UID iRHESUS-VP-XXKXYH (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

299 nt
TCCTATGAGCTGACTCAGTCACCCTCAGTGTCAGTGTCCCCAGGACAGCCAGCCAGCATCACCTGCTCTGGAGATAAATTTGGGAATGCATATGCTTACTGGTACCAGCAGAAGCCAGGCCAGGTCCCTGTACTGGTCATCTATAAAAATAGCAACCGGCCCTCAGGGATCCCTGAGCGATTCTCTGGCTCCAACTCGGGGAACACGGCCACCCTGACCATCAGCGGGGTCGAGGCTGGGGATGAGGCCGACTATTACTGTGCTACAAGCTATGGCAGTGGGAGCAGCTGGCAGTGACT

Amino-acid sequence (V-REGION)

99 aa
SYELTQSPSVSVSPGQPASITCSGDKFGNAYAYWYQQKPGQVPVLVIYKNSNRPSGIPERFSGSNSGNTATLTISGVEAGDEADYYCATSYGSGSSWQ*

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: formerly IGLV3-19*01 (to 2016-12-19);

Allele names i

Every name below denotes this exact sequence (RHESUS-VSPRNIYKC). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGLV22-ACMF*02 IgLabel MUSA, OGRDB
IGLV3-2*01 IMGT IMGT

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
BK063717.1 NCBI accession ncbi_nucleotide

Former IMGT names i

Former nameLast seen in IMGT release
IGLV3-19*012016-12-19

External records i

NCBI nucleotide: link GenBank: GENBANK:BK063717 GenBank: GENBANK:BK063717.1 IMGT: IGLV3-2*01 OGRDB: IGLV22-ACMF*02

Literature references 31 total · 2 verified · 29 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
34875068 verified ncbi_nucleotide
35335026 verified ncbi_nucleotide
25330199 Characteristics of memory B cells elicited by a highly efficacious HPV vaccine in subjects with no pre-existing immunity. name mentioned* literature_supp
25338678 Sequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversity. name mentioned* literature_supp
28813462 A comprehensive profiling of T- and B-lymphocyte receptor repertoires from a Chinese-origin rhesus macaque by high-throughput sequencing. name mentioned* literature_supp
29187855 CD4-Binding Site Directed Cross-Neutralizing scFv Monoclonals from HIV-1 Subtype C Infected Indian Children. name mentioned* literature_supp
29545810 Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification. name mentioned* literature_supp
29558968 BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data. name mentioned* literature_supp
30697215 VH1-69 Utilizing Antibodies Are Capable of Mediating Non-neutralizing Fc-Mediated Effector Functions Against the Transmitted/Founder gp120. name mentioned* literature_supp
31544850 Phage Display Libraries for Antibody Therapeutic Discovery and Development. name mentioned* literature_supp
31816964 Antibody Structure and Function: The Basis for Engineering Therapeutics. name mentioned* literature_supp
31839985 More than one antibody of individual B cells revealed by single-cell immune profiling. name mentioned* literature_supp
33048842 Antimalarial antibody repertoire defined by plasma IG proteomics and single B cell IG sequencing. name mentioned* literature_supp
33180672 Hiding in plain sight: structure and sequence analysis reveals the importance of the antibody DE loop for antibody-antigen binding. name mentioned* literature_supp
33485405 Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD. name mentioned* literature_supp
34242577 In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. name mentioned* literature_supp
34587480 Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses. name mentioned* literature_supp
34741031 Role of mutations and post-translational modifications in systemic AL amyloidosis studied by cryo-EM. name mentioned* literature_supp
35776090 Antibody evolution to SARS-CoV-2 after single-dose Ad26.COV2.S vaccine in humans. name mentioned* literature_supp
36328595 Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing. name mentioned* literature_supp
36611013 Key changes in bovine milk immunoglobulin G during lactation: NeuAc sialylation is a hallmark of colostrum immunoglobulin G N-glycosylation. name mentioned* literature_supp
36827454 Modeling and predicting the overlap of B- and T-cell receptor repertoires in healthy and SARS-CoV-2 infected individuals. name mentioned* literature_supp
37076511 Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages. name mentioned* literature_supp
37520549 Role of the mechanisms for antibody repertoire diversification in monoclonal light chain deposition disorders: when a friend becomes foe. name mentioned* literature_supp
38205245 Comprehensive characterization and database construction of immune repertoire in the largest Chinese glioma cohort. name mentioned* literature_supp
38435425 Analysis of immunoglobulin/T-cell receptor repertoires by high-throughput RNA sequencing reveals a continuous dynamic of positive clonal selection in follicular lymphoma. name mentioned* literature_supp
38707998 Maintenance of caecal homeostasis by diverse adaptive immune cells in the rhesus macaque. name mentioned* literature_supp
40664667 High-resolution mapping of single cells in spatial context. name mentioned* literature_supp
40710355 Pathogenesis of Graves' Disease Determined Using Single-Cell Sequencing with Thyroid Autoantigen Peptide Stimulation in B Cells. name mentioned* literature_supp
41803327 IFN-gene signatures in B cells following influenza A and B virus infection and influenza vaccination. name mentioned* literature_supp
41941497 Pigs lacking Natural Killer T cells have altered cellular responses to influenza. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, MUSA, OGRDB, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTAACACGAACAGATGGAGACATGGGACAGAAACC IMGT MUSA RHESUS-RZUER3

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGCCTGGACGCCTCTCCTCCTCAGCCTCCTCGCTCACTGCACAGGCTCTGTGGCC 46 + 11 nt IMGT RHESUS-LHFEFE
ATGGCCTGGACGCCTCTCCTCCTCAGCCTCCTCGCTCACTGCACAGGTGCTCTGTGGCC 48 + 11 nt MUSA RHESUS-LSGHCB

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/RHESUS-VSPRNIYKC/similar?min_identity=0.95&kind=nt.