RHESUS-VSYTZHFTO

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMacaca mulatta LocusIGH TypeV FunctionalTrue Length299 nt

Species	Macaca mulatta (NCBITAXON:9544)
Locus / type	IGH / V
Functional i	True
Length	299 nt
Protein UID i	RHESUS-VP-YFMOQF (shared by alleles with the same V-REGION amino-acid sequence)

Allele names i

Every name below denotes this exact sequence (RHESUS-VSYTZHFTO). None is canonical; they are labels, and the UID is the key.

Multiple allele designations. This one sequence is recorded under 3 different allele designations: IGHV4-106*01, IGHV4-79*01, IGHV4-AFB*01. These are identical normalized nucleotide sequences with different attributed names.

Name	Scheme	Source(s)
IGHV4-ABR2*02	IgLabel	MUSA, OGRDB
IGHV4-106*01	IMGT	IMGT
IGHV4-79*01	KIMDB	KIMDB
IGHV4-AFB*01	RhGLDB+	RhGLDB+

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

Name	Kind	Source(s)
BK063715.1	NCBI accession	ncbi_nucleotide

External records i

genbank:MF989460: GENBANK:MF989460 NCBI nucleotide: link GenBank: GENBANK:BK063715 GenBank: GENBANK:BK063715.1 IMGT: IGHV4-106*01 OGRDB: IGHV4-ABR2*02

Literature references 10 total · 4 verified · 4 sequence-in-paper · 2 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMID	Title	Evidence	Source
29163486		verified	MUSA
31080066		verified	MUSA
34875068		verified	ncbi_nucleotide
35335026		verified	ncbi_nucleotide
32866207	Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.	sequence in paper	literature_supp
35419009	Addressing IGHV Gene Structural Diversity Enhances Immunoglobulin Repertoire Analysis: Lessons From Rhesus Macaque.	sequence in paper	literature_supp
38707998	Maintenance of caecal homeostasis by diverse adaptive immune cells in the rhesus macaque.	sequence in paper	literature_supp
39068149	Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques.	sequence in paper	literature_supp
36405682	Primary antibody response after influenza virus infection is first dominated by low-mutated HA-stem antibodies followed by higher-mutated HA-head antibodies.	name mentioned^*	literature_supp
41392054	Necessity of individual VDJ-databases for annotating antibody heavy chain characteristics in non-human primates.	name mentioned^*	literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, KIMDB, MUSA, OGRDB, RhGLDB+, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

Part	Sequence	Source	RSS UID
v_rs	CACAGTGAGGGGAGGTGGGTGTGAGCCCAGACACAAACC	MUSA	RHESUS-RRLVV2
v_rs	CACAGTGAGGGGAGGTGAGTGTGAGCCCAGACACAAACC	IMGT MUSA	RHESUS-RXT2LD

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)	Split	Source	Leader UID
ATGAAGCACCTGTGGTTCTTCCTCCTCCTGGTGGCAGCTCCCAGATGGGTCTTGTCC	46 + 11 nt	IMGT	RHESUS-LA77B4
ATGAAGCACCTGTGGTTCTTCCTCCTCCTGGTGGCAGCTCCCAGATGTGGGTCCTGTCC	48 + 11 nt	MUSA	RHESUS-LIUYTJ
ATGAAGCACCTGTGGTTCTTCCTCCTCCTGGTGGCAGCTCCCAGATGTGGGTCTTGTCC	48 + 11 nt	MUSA	RHESUS-LVSYWT

Find similar alleles

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/RHESUS-VSYTZHFTO/similar?min_identity=0.95&kind=nt.

Coding sequence (nt)

299 nt

CAGGTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCGCTGTCTCTGGTGGCTCCATCAGCGATGATTACTACTGGAGCTGGATCCGCCAGCCCCCAGGGAAGGGACTGGAGTGGATTGGGTACATCTATGGTAGTGGTGGGGGCACCAACTACAATCCCTCCCTCAAGAATCGAGTCACCATTTCAATAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCGGACACGGCCGTGTATTACTGTGCGAGAGA

Amino-acid sequence (V-REGION)

99 aa

QVQLQESGPGLVKPSETLSLTCAVSGGSISDDYYWSWIRQPPGKGLEWIGYIYGSGGGTNYNPSLKNRVTISIDTSKNQFSLKLSSVTAADTAVYYCAR

Published by the source, and consistent with the nucleotide sequence above. i

API: JSON · AIRR AlleleDescription · aliases