AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

← back to search

RHESUS-VVZT2AYGA

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMacaca mulatta LocusIGH TypeV FunctionalTrue Length296 nt
SpeciesMacaca mulatta (NCBITAXON:9544)
Locus / typeIGH / V
Functional iTrue
Length296 nt
Protein UID iRHESUS-VP-FRRIQK (shared by alleles with the same V-REGION amino-acid sequence)

Allele names i

Every name below denotes this exact sequence (RHESUS-VVZT2AYGA). None is canonical; they are labels, and the UID is the key.

Multiple allele designations. This one sequence is recorded under 3 different allele designations: IGHV1S2*01, IGHV1-105*01, IGHV1-AFS*01. These are identical normalized nucleotide sequences with different attributed names.

NameSchemeSource(s)
IGHV1-JHF7*01 IgLabel MUSA, OGRDB
IGHV1S2*01 IMGT IMGT
IGHV1-105*01 KIMDB KIMDB
IGHV1-AFS*01 RhGLDB+ RhGLDB+

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
NW_001122023.1 NCBI accession ncbi_nucleotide

External records i

genbank:MF989477: GENBANK:MF989477 NCBI nucleotide: link NCBI Gene: NCBIGENE:720866 GenBank: GENBANK:NW_001122023 IMGT: IGHV1S2*01 OGRDB: IGHV1-JHF7*01

Literature references 6 total · 2 verified · 2 sequence-in-paper · 2 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
29163486 verified MUSA
31080066 verified MUSA
32866207 Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. sequence in paper literature_supp
35419009 Addressing IGHV Gene Structural Diversity Enhances Immunoglobulin Repertoire Analysis: Lessons From Rhesus Macaque. sequence in paper literature_supp
35709309 Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4. name mentioned* literature_supp
38042809 Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, KIMDB, MUSA, OGRDB, RhGLDB+, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGTGAAAACCACATCCTGAGAGTGTCAGAAACC IMGT MUSA RHESUS-R64W3P

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGACTGGATATGGAGGATCCTCCTCTTGGTGGCAGCAGCTACAGGTGCGCCCACTCC 48 + 11 nt MUSA RHESUS-LDELOF
ATGGACTGGATATGGAGGATCCTCCTCTTGGTGGCAGCAGCTACAGGCGCCCACTCC 46 + 11 nt IMGT RHESUS-LHA2SH

Find similar alleles

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/RHESUS-VVZT2AYGA/similar?min_identity=0.95&kind=nt.

Coding sequence (nt)

296 nt
CAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCAGTGAAGGTATCCTGCAAGGCTTCCGGATACACCTTCACTGACTACTACATGCACTGGGTGCGACAGGCCCCTCGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTTACAATGGCAACACAAAGTATGCACAGAAGTTCCAGGGCAGAGTCACCATGACCAGAGACACATCGACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGAGA

Amino-acid sequence (V-REGION)

98 aa
QVQLVQSGAEVKKPGSSVKVSCKASGYTFTDYYMHWVRQAPRQGLEWMGWINPYNGNTKYAQKFQGRVTMTRDTSTSTAYMELSSLRSEDTAVYYCAR

Published by the source, and consistent with the nucleotide sequence above. i