AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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RHESUS-VYZGAPEGF

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMacaca mulatta LocusIGH TypeV FunctionalTrue Length301 nt
SpeciesMacaca mulatta (NCBITAXON:9544)
Locus / typeIGH / V
Functional iTrue
Length301 nt
Protein UID iRHESUS-VP-JTEM4W (shared by alleles with the same V-REGION amino-acid sequence)

Allele names i

Every name below denotes this exact sequence (RHESUS-VYZGAPEGF). None is canonical; they are labels, and the UID is the key.

Multiple allele designations. This one sequence is recorded under 4 different allele designations: IGHV2-95*01, IGHV2-69*01, LJI.Rh_IGHV2.69, IGHV2-AEY-S*02_S1242. These are identical normalized nucleotide sequences with different attributed names.

NameSchemeSource(s)
IGHV2-5KIN*12 IgLabel MUSA
IGHV2-5VX5*13 IgLabel OGRDB
IGHV2-95*01 IMGT IMGT
IGHV2-69*01 KIMDB KIMDB
LJI.Rh_IGHV2.69 RhGLDB+ RhGLDB+
IGHV2-AEY-S*02_S1242 VRC VRC

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
BK063715.1 NCBI accession ncbi_nucleotide

External records i

NCBI nucleotide: link GenBank: GENBANK:BK063715 GenBank: GENBANK:BK063715.1 IMGT: IGHV2-95*01 OGRDB: IGHV2-5VX5*13

Literature references 7 total · 3 verified · 2 sequence-in-paper · 2 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
31080066 verified MUSA
34875068 verified ncbi_nucleotide
35335026 verified ncbi_nucleotide
32866207 Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. sequence in paper literature_supp
35419009 Addressing IGHV Gene Structural Diversity Enhances Immunoglobulin Repertoire Analysis: Lessons From Rhesus Macaque. sequence in paper literature_supp
36405682 Primary antibody response after influenza virus infection is first dominated by low-mutated HA-stem antibodies followed by higher-mutated HA-head antibodies. name mentioned* literature_supp
41392054 Necessity of individual VDJ-databases for annotating antibody heavy chain characteristics in non-human primates. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, KIMDB, MUSA, OGRDB, RhGLDB+, VRC, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGAGACACAGCCCAGGGCGCCTCCTGTACAAGAACC IMGT MUSA RHESUS-R5MGF5

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGACACGCTTTGCTACACACTCCTGCTACTGACCGTCCCGTCCTGTGGGTCTTGTCC 48 + 11 nt MUSA RHESUS-LAMHJA
ATGGACACGCTTTGCTACACACTCCTGCTACTGACCGTCCCGTCCTGGGTCTTGTCC 46 + 11 nt IMGT RHESUS-LDYR6A

Find similar alleles

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/RHESUS-VYZGAPEGF/similar?min_identity=0.95&kind=nt.

Coding sequence (nt)

301 nt
CAGGTCACCTTGAAGGAGTCTGGTCCTGCGCTCGTGAAACCCACACAGACCCTCACGCTGACCTGCACCTTCTCTGGGTTCTCAATCAGCACTACTGGAACAGGTGTGGGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAATGGCTTGCAAGCATTTATTGGAATGATAGTAAATACTACAGCACATCGCTGAAGAGCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTTCTAACAATGACCAACATGGACCCTGTGGACACAGCCACATATTACTGTGCACGGGTAC

Amino-acid sequence (V-REGION)

100 aa
QVTLKESGPALVKPTQTLTLTCTFSGFSISTTGTGVGWIRQPPGKALEWLASIYWNDSKYYSTSLKSRLTISKDTSKNQVVLTMTNMDPVDTATYYCARV

Published by the source, and consistent with the nucleotide sequence above. i