AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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RHESUS-VZ4WLDL2S

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesMacaca mulatta LocusIGL TypeV FunctionalTrue Length297 nt

IGLV2-26*02, IGLV2-ADK*01: a Macaca mulatta IGL V allele sequence, 297 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesMacaca mulatta (NCBITAXON:9544)
Locus / typeIGL / V
Functional iTrue
Length297 nt
Protein UID iRHESUS-VP-KELBFE (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

297 nt
CAGGCTGCCCTGACTCAGCCTCCCTCAGTGTCCAAGTCTCTTGGACAGTCGGTCACCATCTCCTGCGCTGGAACCAGCAGTGGCATTGCTAGTTATAGTGACGTCTCCTGGTACCAGCAGCACCCAGGCACAGCCCCCAGACTCCTGATTTACCGTGTCAGTAATCGACCCTCAGGGGTCTCTGATCGCTTCTCTGGCTTCAAGTCTGGCAGCACAGCCTCCCTGACCATCTCTGGGCTCCAGGCTGAGGACGAGGCTATTTATTACTGCTGCTCATATAGGAGTGGAAGCACTTTC

Amino-acid sequence (V-REGION)

99 aa
QAALTQPPSVSKSLGQSVTISCAGTSSGIASYSDVSWYQQHPGTAPRLLIYRVSNRPSGVSDRFSGFKSGSTASLTISGLQAEDEAIYYCCSYRSGSTF

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: formerly IGLV2-5*01 (to 2019-03-01);

Allele names i

Every name below denotes this exact sequence (RHESUS-VZ4WLDL2S). None is canonical; they are labels, and the UID is the key.

Multiple allele designations. This one sequence is recorded under 2 different allele designations: IGLV2-26*02, IGLV2-ADK*01. These are identical normalized nucleotide sequences with different attributed names.

NameSchemeSource(s)
IGLV2-4HKX*02 IgLabel MUSA
IGLV2-M5CD*03 IgLabel OGRDB
IGLV2-26*02 IMGT IMGT
IGLV2-ADK*01 RhGLDB+ RhGLDB+

Other names & identifiers

Alternative and former names, e.g. IMGT clone names, plus accession identifiers.

NameKindSource(s)
NW_001095158.1 NCBI accession ncbi_nucleotide

Former IMGT names i

Former nameLast seen in IMGT release
IGLV2-5*012019-03-01

External records i

genbank:MF989453: GENBANK:MF989453 genbank:IMGT000062: GENBANK:IMGT000062 NCBI nucleotide: link GenBank: GENBANK:NW_001095158 IMGT: IGLV2-26*02 OGRDB: IGLV2-M5CD*03

Literature references 8 total · 2 verified · 2 sequence-in-paper · 4 name-mentioned* i

PubMed publications linked to this allele. A sequence-in-paper match indicates that this allele's exact sequence was detected in the publication text or supplementary material; it is sequence-level evidence. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
29163486 verified MUSA
31080066 verified MUSA
32866207 Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. sequence in paper literature_supp
39068149 Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques. sequence in paper literature_supp
31839985 More than one antibody of individual B cells revealed by single-cell immune profiling. name mentioned* literature_supp
36328595 Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing. name mentioned* literature_supp
37076511 Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages. name mentioned* literature_supp
38042809 Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT, MUSA, OGRDB, RhGLDB+, ncbi_nucleotide. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGGTCCAATTTCATGAGGAACTGAGACCAAAACC IMGT MUSA RHESUS-RSGRHC

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGCCTGGGCTCTGCTCCTCCTCACCCTTCTCACTCAAGGCACAGGATCCTGGGCT 46 + 11 nt IMGT RHESUS-LOZTBP
ATGGCCTGGGCTCTGCTCCTCCTCACCCTTCTCACTCAAGGCACAGGCGATCCTGGGCT 48 + 11 nt MUSA RHESUS-LXNGT6

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/RHESUS-VZ4WLDL2S/similar?min_identity=0.95&kind=nt.