SHEEP-VE43WY3BT
AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.
TRBV14*01: a Ovis aries TRB V allele sequence, 290 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.
| Species | Ovis aries (NCBITAXON:9940) |
|---|---|
| Locus / type | TRB / V |
| Functional i | True |
| Length | 290 nt |
| Protein UID i | SHEEP-VP-3IAQTT (shared by alleles with the same V-REGION amino-acid sequence) |
Coding sequence (nt)
Amino-acid sequence (V-REGION)
Published by the source, and consistent with the nucleotide sequence above. i
Name history i: stable — no former names, re-cuts, or archival on record.
Allele names i
Every name below denotes this exact sequence (SHEEP-VE43WY3BT). None is canonical; they are labels, and the UID is the key.
| Name | Scheme | Source(s) |
|---|---|---|
| TRBV14*01 | IMGT | IMGT |
External records i
IMGT: TRBV14*01
Literature references i
PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.
| PMID | Title | Evidence | Source |
|---|---|---|---|
| 22792299 | Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets. | name mentioned* | literature_supp |
| 26962778 | High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire. | name mentioned* | literature_supp |
| 27460926 | Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq. | name mentioned* | literature_supp |
| 30541895 | Autoimmunity to hypocretin and molecular mimicry to flu in type 1 narcolepsy. | name mentioned* | literature_supp |
| 31237075 | Comparative analysis of CDR3 regions in paired human αβ CD8 T cells. | name mentioned* | literature_supp |
| 32868763 | Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells. | name mentioned* | literature_supp |
| 34845983 | TCR meta-clonotypes for biomarker discovery with tcrdist3 enabled identification of public, HLA-restricted clusters of SARS-CoV-2 TCRs. | name mentioned* | literature_supp |
| 36408799 | SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells. | name mentioned* | literature_supp |
| 36603583 | Improved predictions of antigen presentation and TCR recognition with MixMHCpred2.2 and PRIME2.0 reveal potent SARS-CoV-2 CD8+ T-cell epitopes. | name mentioned* | literature_supp |
| 36923729 | Cross-reactivity influences changes in human influenza A virus and Epstein Barr virus specific CD8 memory T cell receptor alpha and beta repertoires between young and old. | name mentioned* | literature_supp |
| 38762584 | Invariant γδTCR natural killer-like effector T cells in the naked mole-rat. | name mentioned* | literature_supp |
| 38871688 | Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas. | name mentioned* | literature_supp |
| 38878776 | Quantifiable TCR repertoire changes in prediagnostic blood specimens among patients with high-grade ovarian cancer. | name mentioned* | literature_supp |
| 39133650 | Expansion of the HSV-2-specific T cell repertoire in skin after immunotherapeutic HSV-2 vaccine. | name mentioned* | literature_supp |
| 39421738 | scRNA+TCR-seq reveals the pivotal role of dual receptor T lymphocytes in the pathogenesis of Kawasaki disease and during IVIG treatment. | name mentioned* | literature_supp |
| 39472557 | Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes. | name mentioned* | literature_supp |
| 40664667 | High-resolution mapping of single cells in spatial context. | name mentioned* | literature_supp |
| 40866291 | Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer. | name mentioned* | literature_supp |
| 41150899 | Large-Scale T-cell Receptor Repertoire Profiling Unveils Tumor-Specific Signals for Diagnosing Indeterminate Pulmonary Nodules. | name mentioned* | literature_supp |
| 41407706 | Resistance potential of the HLA-A2-restricted immunodominant SARS-CoV-2-specific CD8+ T cell receptor repertoire to antigenic drift. | name mentioned* | literature_supp |
| 41424382 | Identification of Sjögren's disease-associated T cell receptor motifs through deep sequencing. | name mentioned* | literature_supp |
| 42129543 | One-step generation of T-cell receptor knock-in mice in the TCRβ locus. | name mentioned* | literature_supp |
* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.
Contributed by IMGT. See Sources & citations for each source's version, citation and licence.
RSS i
Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.
| Part | Sequence | Source | RSS UID |
|---|---|---|---|
| v_rs | CACAGTGCTTCAGAGTTCTGTCCTTGCTGTGCAAAACCA | IMGT | SHEEP-ROIMQ6 |
Leader
Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.
| Leader (exon 1 + exon 2) | Split | Source | Leader UID |
|---|---|---|---|
| ATGTTCTCCAGGCTTCTCCGCTTAGCGTCGCTGTGTCTCCTGGGAGCAAGGTACATA | 49 + 8 nt | IMGT | SHEEP-LPGESB |
Find similar (nt · aa · cross-species) i
Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.
Ranks coding alleles by normalized edit-distance identity.
Also available at /api/sequences/SHEEP-VE43WY3BT/similar?min_identity=0.95&kind=nt.
API: JSON · AIRR AlleleDescription · aliases