AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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COW-VY42SWAXB

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesBos taurus LocusIGH TypeV FunctionalTrue Length293 nt

IGHV1-37*01: a Bos taurus IGH V allele sequence, 293 nt, functional. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesBos taurus (NCBITAXON:9913)
Locus / typeIGH / V
Functional iTrue
Length293 nt
Protein UID iCOW-VP-BPR6VC (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

293 nt
CAGGTGCAGCTGCAGGAGTCGGGCCCCAGCCTGGTGAAGACCTCACAGACACTCTCCCTCACTTGCACGGCCTCTGGATTATCATTAACCAGATATGGTATACACTGGGTCCGCCAGGCTCCAGGAAAGGCGCTGGAGTGGCTTGGTGATATAAGCAGTGGTGGAAGCACAGGCTATAACCCAGGCCTGAAATCCCGGCTCAGCATCACCAAGGACAACTCCAAGAGCCAAGTCTCTCTGTCACTGAGCAGCCTGACGCCTGAGGACTCAGCCACATACTACTGTGCAAGAGA

Amino-acid sequence (V-REGION)

97 aa
QVQLQESGPSLVKTSQTLSLTCTASGLSLTRYGIHWVRQAPGKALEWLGDISSGGSTGYNPGLKSRLSITKDNSKSQVSLSLSSLTPEDSATYYCAR

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (COW-VY42SWAXB). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV1-37*01 IMGT IMGT

External records i

IMGT: IGHV1-37*01

Literature references 4 total · 4 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
29545810 Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification. name mentioned* literature_supp
39698082 Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten. name mentioned* literature_supp
40338637 Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein. name mentioned* literature_supp
41410768 Convergent mutation trajectories convert functional self-tolerance in IGHV4-34 B cells to genetic tolerance encoded in the antibody. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGAGGGGAAGTCAGTGTGAGCCCAGACAAAAACC IMGT COW-RKD7B5

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGAACCCACTGTGGACCCTCCTCTTTGTGCTGTCAGCCCCCAGAGGCGTCCTGTCC 46 + 11 nt IMGT COW-LHJBKS

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/COW-VY42SWAXB/similar?min_identity=0.95&kind=nt.