AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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ORANGSUM-VLD65CSKQ

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesPongo abelii LocusTRB TypeV FunctionalNone Length287 nt

TRBV6-6*03: a Pongo abelii TRB V allele sequence, 287 nt, not recorded. The nucleotide and amino-acid sequence is below, with every recorded name and its source.

SpeciesPongo abelii (NCBITAXON:9601)
Locus / typeTRB / V
Functional iNone
Length287 nt
Protein UID iORANGSUM-VP-27LLGJ (shared by alleles with the same V-REGION amino-acid sequence)

Coding sequence (nt)

287 nt
AATGCCGGTGTCACTCAGACCCCAAAATTCCATGTCCTGAAGACAGGACAGAGCATGACACTGCAGTGTGCCCAGGATATGAACCATGACTACATGTCCTGGTATTGACAAGACCCAGGCATGGGGCTGAGGCTGATTCATTACTCAGCTGGTGCTGGTATCACTGACAAAGGAGAAGTCCCCAATGGCTACAATGTCTCCAGATTAAACACGGAGGATTTCCAGCTCAGACTGGAGTCAGCTGCTCCCTCCCAGACATCTGTGTACTTCTGTGCCAGCAGTTACTC

Amino-acid sequence (V-REGION)

95 aa
NAGVTQTPKFHVLKTGQSMTLQCAQDMNHDYMSWY*QDPGMGLRLIHYSAGAGITDKGEVPNGYNVSRLNTEDFQLRLESAAPSQTSVYFCASSY

Published by the source, and consistent with the nucleotide sequence above. i

Name history i: stable — no former names, re-cuts, or archival on record.

Allele names i

Every name below denotes this exact sequence (ORANGSUM-VLD65CSKQ). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
TRBV6-6*03 IMGT IMGT

External records i

IMGT: TRBV6-6*03

Literature references 8 total · 8 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
22792299 Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets. name mentioned* literature_supp
26962778 High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire. name mentioned* literature_supp
31237075 Comparative analysis of CDR3 regions in paired human αβ CD8 T cells. name mentioned* literature_supp
35436998 pmTR database: population matched (pm) germline allelic variants of T-cell receptor (TR) loci. name mentioned* literature_supp
36778049 Targeted long-read sequencing facilitates phased diploid assembly and genotyping of the human T cell receptor alpha, delta, and beta loci. name mentioned* literature_supp
36923729 Cross-reactivity influences changes in human influenza A virus and Epstein Barr virus specific CD8 memory T cell receptor alpha and beta repertoires between young and old. name mentioned* literature_supp
38336680 NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route. name mentioned* literature_supp
39472557 Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGCGCTGCAAGGCTGTCTCCTCTCTGCACATAAAGG IMGT ORANGSUM-RPS4JV

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGAGCATCGGCCTCCTGTGCTGTGCAGCCTTTTTTCTCCTGTGGGCAGGTCCAGTG 49 + 8 nt IMGT ORANGSUM-LDKS2W

Find similar (nt · aa · cross-species) i

Everything comparative about this sequence (the exact differences to other alleles, protein consequence, IMGT alignment, cross-species nearest) is shown per hit in the results of this query.

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/ORANGSUM-VLD65CSKQ/similar?min_identity=0.95&kind=nt.