AIRBabel immunoglobulin and T-cell receptor allele sequences · leaders · RSSs

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ORANGSUM-VO6AP75C4

AIRBabel's deterministic identifier, minted from the sequence (SPECIES-CODE+hash) i: a stable sequence-derived identifier, not an official allele name. This sequence's names from each source are listed under Allele names.

SpeciesPongo abelii LocusIGH TypeV FunctionalTrue Length296 nt
SpeciesPongo abelii (NCBITAXON:9601)
Locus / typeIGH / V
Functional iTrue
Length296 nt
Protein UID iORANGSUM-VP-SA4RJI (shared by alleles with the same V-REGION amino-acid sequence)

Allele names i

Every name below denotes this exact sequence (ORANGSUM-VO6AP75C4). None is canonical; they are labels, and the UID is the key.

NameSchemeSource(s)
IGHV1-54*01 IMGT IMGT

External records i

IMGT: IGHV1-54*01

Literature references 7 total · 7 name-mentioned* i

PubMed publications linked to this allele. Name-mentioned entries were auto-collected by name match and may refer to a different same-named allele; treat them as leads, not ground truth.

PMIDTitleEvidenceSource
32326443 Exploration and Modulation of Antibody Fragment Biophysical Properties by Replacing the Framework Region Sequences. name mentioned* literature_supp
36473496 Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination. name mentioned* literature_supp
36604758 Bacteroides-derived isovaleric acid enhances mucosal immunity by facilitating intestinal IgA response in broilers. name mentioned* literature_supp
39127707 Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonally and functionally restricted. name mentioned* literature_supp
39698082 Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten. name mentioned* literature_supp
40338637 Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein. name mentioned* literature_supp
41410768 Convergent mutation trajectories convert functional self-tolerance in IGHV4-34 B cells to genetic tolerance encoded in the antibody. name mentioned* literature_supp

* matched by allele name only. The publication mentions this name, but AIRBabel cannot determine from the name alone whether it refers to this allele; the same name can denote a different allele in another species. This is useful for literature review but is not verified evidence.

Contributed by IMGT. See Sources & citations for each source's version, citation and licence.

RSS i

Recombination signal sequences flanking this allele. Click one to see every coding allele linked to that exact RSS variant.

PartSequenceSourceRSS UID
v_rsCACAGTGTGAAAACCCACATCCTGAGAGTGTCAGAAACC IMGT ORANGSUM-RNTBEN

Leader

Signal-peptide coding sequence (spliced exon 1 + exon 2). The genomic intron between the two exons is deferred.

Leader (exon 1 + exon 2)SplitSourceLeader UID
ATGGACTGGACCTGGAGGATCCTGTTCTTGATGGCAGCAGCTACAGGTGCCCACTCC 46 + 11 nt IMGT ORANGSUM-LUVYZO

Find similar alleles

Ranks coding alleles by normalized edit-distance identity. Also available at /api/sequences/ORANGSUM-VO6AP75C4/similar?min_identity=0.95&kind=nt.

Coding sequence (nt)

296 nt
CATGTCCAATTGGTGCAGTCTGGGGATGAGGTGAGGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCAACCACAACATGGACTGGGTGCGACAGGCCCCTGGACAAGGGTTTGAGTGGATGGGAGGGATCAACACTAACACTGGTGGCACAAGCTATGCACAGACTTTCCAGGGCAGAGTCATCATGACGAGGGACACGTCCACAAACACAGCCTTCATGGAGCTGAGCAGCCTGAGATCTGAGGACATGACTGTGTATTACTGTGCAAGAGA

Amino-acid sequence (V-REGION)

98 aa
HVQLVQSGDEVRKPGASVKVSCKASGYTFTNHNMDWVRQAPGQGFEWMGGINTNTGGTSYAQTFQGRVIMTRDTSTNTAFMELSSLRSEDMTVYYCAR

Published by the source, and consistent with the nucleotide sequence above. i